PDB entry 6fc7

View 6fc7 on RCSB PDB site
Description: crystal structure of two-domain laccase mutant h165f from streptomyces griseoflavus with high copper ions occupancy
Deposited on 2017-12-20, released 2019-01-30
The last revision was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Two-domain laccase
    Species: Streptomyces griseoflavus [TaxId:35619]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CU, PER, GOL, OXY, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fc7A (A:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7A (A:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydpqeh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6fc7B (B:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7B (B:)
gaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvpv
slhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdhv
vgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrv
eivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegv
gagawmyhchvqshsdmgmvglflvkkpdgtipgydpqeha

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6fc7C (C:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7C (C:)
gaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvpv
slhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdhv
vgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrv
eivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegv
gagawmyhchvqshsdmgmvglflvkkpdgtipgydp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6fc7D (D:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7D (D:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6fc7E (E:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7E (E:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6fc7F (F:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7F (F:)
gaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvpv
slhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdhv
vgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrv
eivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegv
gagawmyhchvqshsdmgmvglflvkkpdgtipgydp

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6fc7G (G:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7G (G:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydpqeh

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6fc7H (H:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7H (H:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydp

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6fc7I (I:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7I (I:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydpqeh

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6fc7J (J:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7J (J:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydpqeh

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6fc7K (K:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7K (K:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgydpqeha

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6fc7L (L:)
mdrrgfnrrvllggvaattslsiapeavsapesagtaaaagaapaggevrrvtmyaerla
ggqmgyglekgkasipgplielnegdtlhvefentmdvpvslhvhgldyeissdgtkqnk
shvepggtrtytwrthepgrradgtwragsagywhyhdhvvgtefgtggirnglygpviv
rrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdrveivmithgeyyhtfhmhghr
wadnrtgmltgpddpsqvidnkicgpadsfgfqiiagegvgagawmyhchvqshsdmgmv
glflvkkpdgtipgydpqehah

    Sequence, based on observed residues (ATOM records):
    >6fc7L (L:)
agaapaggevrrvtmyaerlaggqmgyglekgkasipgplielnegdtlhvefentmdvp
vslhvhgldyeissdgtkqnkshvepggtrtytwrthepgrradgtwragsagywhyhdh
vvgtefgtggirnglygpvivrrkgdvlpdathtivfndmtinnrpahtgpnfeatvgdr
veivmithgeyyhtfhmhghrwadnrtgmltgpddpsqvidnkicgpadsfgfqiiageg
vgagawmyhchvqshsdmgmvglflvkkpdgtipgy