PDB entry 6f6t

View 6f6t on RCSB PDB site
Description: Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum complexed with S-APPA
Class: lyase
Keywords: Inhibitor, Complex, Phenylalanine ammonia-lyase, LYASE
Deposited on 2017-12-06, released 2019-06-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine ammonia-lyase 1
    Species: Petroselinum crispum [TaxId:4043]
    Gene: PAL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24481 (Start-715)
      • chromophore (202)
      • engineered mutation (703)
      • engineered mutation (715)
    Domains in SCOPe 2.08: d6f6ta_
  • Chain 'B':
    Compound: phenylalanine ammonia-lyase 1
    Species: Petroselinum crispum [TaxId:4043]
    Gene: PAL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24481 (Start-715)
      • chromophore (202)
      • engineered mutation (703)
      • engineered mutation (715)
    Domains in SCOPe 2.08: d6f6tb_
  • Heterogens: MDO, CV2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6f6tA (A:)
mengngattnghvngngmdfcmktedplywgiaaeamtgshldevkkmvaeyrkpvvklg
getltisqvaaisardgsgvtvelseaaragvkassdwvmdsmnkgtdsygvttgfgats
hrrtkqggalqkelirflnagifgngsdntlphsatraamlvrintllqgysgirfeile
aitkflnqnitpclplrgtitasgdlvplsyiaglltgrpnskavgptgvilspeeafkl
agveggffelqpkeglalvngtavgsgmasmvlfeanilavlaevmsaifaevmqgkpef
tdhlthklkhhpgqieaaaimehildgsayvkaaqklhemdplqkpkqdryalrtspqwl
gpqievirsstkmiereinsvndnplidvsrnkaihggnfqgtpigvsmdntrlaiaaig
klmfaqfselvndfynnglpsnlsggrnpsldygfkgaeiamasycselqflanpvtnhv
qsaeqhnqdvnslglissrktseaveilklmsttflvglcqaidlrhleenlkstvkntv
ssvakrvltmgvngelhpsrfcekdllrvvdreyifayiddpcsatyplmqklrqtlveh
alkngdnernlstsifqkiatfedelkallpkevesaraalesgnpaipnrieecrsypl
ykfvrkelgteyltgekvtspgeefekvfiamskgeiidpllesleswngaplpis

    Sequence, based on observed residues (ATOM records): (download) 
    >6f6tA (A:)
edplywgiaaeamtgshldevkkmvaeyrkpvvklggetltisqvaaisardgsgvtvel
seaaragvkassdwvmdsmnkgtdsygvttgfgatshrrtkqggalqkelirflnagifg
ngsdntlphsatraamlvrintllqgysgirfeileaitkflnqnitpclplrgtitasg
dlvplsyiaglltgrpnskavgptgvilspeeafklagveggffelqpkeglalvngtav
gsgmasmvlfeanilavlaevmsaifaevmqgkpeftdhlthklkhhpgqieaaaimehi
ldgsayvkaaqklpkqdryalrtspqwlgpqievirsstkmiereinsvndnplidvsrn
kaihggnfqgtpigvsmdntrlaiaaigklmfaqfselvndfynnglpsnlsggrnpsld
ygfkgaeiamasycselqflanpvtnhvqsaeqhnqdvnslglissrktseaveilklms
ttflvglcqaidlrhleenlkstvkntvssvakrvlthpsrfcekdllrvvdreyifayi
ddpcsatyplmqklrqtlvehalkngdnernlstsifqkiatfedelkallpkevesara
alesgnpaipnrieecrsyplykfvrkelgteyltgekvtspgeefekvfiamskgeiid
pllesleswngaplpis

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6f6tB (B:)
mengngattnghvngngmdfcmktedplywgiaaeamtgshldevkkmvaeyrkpvvklg
getltisqvaaisardgsgvtvelseaaragvkassdwvmdsmnkgtdsygvttgfgats
hrrtkqggalqkelirflnagifgngsdntlphsatraamlvrintllqgysgirfeile
aitkflnqnitpclplrgtitasgdlvplsyiaglltgrpnskavgptgvilspeeafkl
agveggffelqpkeglalvngtavgsgmasmvlfeanilavlaevmsaifaevmqgkpef
tdhlthklkhhpgqieaaaimehildgsayvkaaqklhemdplqkpkqdryalrtspqwl
gpqievirsstkmiereinsvndnplidvsrnkaihggnfqgtpigvsmdntrlaiaaig
klmfaqfselvndfynnglpsnlsggrnpsldygfkgaeiamasycselqflanpvtnhv
qsaeqhnqdvnslglissrktseaveilklmsttflvglcqaidlrhleenlkstvkntv
ssvakrvltmgvngelhpsrfcekdllrvvdreyifayiddpcsatyplmqklrqtlveh
alkngdnernlstsifqkiatfedelkallpkevesaraalesgnpaipnrieecrsypl
ykfvrkelgteyltgekvtspgeefekvfiamskgeiidpllesleswngaplpis

    Sequence, based on observed residues (ATOM records): (download) 
    >6f6tB (B:)
tedplywgiaaeamtgshldevkkmvaeyrkpvvklggetltisqvaaisardgsgvtve
lseaaragvkassdwvmdsmnkgtdsygvttgfgatshrrtkqggalqkelirflnagif
gngsdntlphsatraamlvrintllqgysgirfeileaitkflnqnitpclplrgtitas
gdlvplsyiaglltgrpnskavgptgvilspeeafklagveggffelqpkeglalvngta
vgsgmasmvlfeanilavlaevmsaifaevmqgkpeftdhlthklkhhpgqieaaaimeh
ildgsayvkapkqdryalrtspqwlgpqievirsstkmiereinsvndnplidvsrnkai
hggnfqgtpigvsmdntrlaiaaigklmfaqfselvndfynnglpsnlsggrnpsldygf
kgaeiamasycselqflanpvtnhvqsaeqhnqdvnslglissrktseaveilklmsttf
lvglcqaidlrhleenlkstvkntvssvakrvltmggelhpsrfcekdllrvvdreyifa
yiddpcsatyplmqklrqtlvehalkngdnernlstsifqkiatfedelkallpkevesa
raalesgnpaipnrieecrsyplykfvrkelgteyltgekvtspgeefekvfiamskgei
idpllesleswngaplpis