PDB entry 6f5q

View 6f5q on RCSB PDB site
Description: Crystal Structure of KDM4D with GF026 ligand
Class: oxidoreductase
Keywords: KDM4D, KDM4, ligand binding, ligand optimization, drug development, inhibitor design, cancer, epigenetics, OXIDOREDUCTASE
Deposited on 2017-12-02, released 2018-12-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-12-12, with a file datestamp of 2018-12-07.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific demethylase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: KDM4D, JHDM3D, JMJD2D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6f5qa_
  • Heterogens: ZN, CL, EDO, SO4, NI, CTK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6f5qA (A:)
    metmkskancaqnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkar
    etydniseiliatplqqvasgragvftqyhkkkkamtvgeyrhlanskkyqtpphqnfed
    lerkywknriynspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpyl
    yfgmwkttfawhtedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcga
    flrhkvalisptvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprw
    idygkmasqcscgearvtfsmdafvrilqperydlwkrgqdr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6f5qA (A:)
    aqnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkaretydniseil
    iatplqqvasgragvftqyhkkkkamtvgeyrhlanskkyqtpphqnfedlerkywknri
    ynspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpylyfgmwkttfa
    whtedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcgaflrhkvalis
    ptvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprwidygkmasqc
    scgearvtfsmdafvrilqperydlwkrgq