PDB entry 6f5m

View 6f5m on RCSB PDB site
Description: Crystal structure of highly glycosylated human leukocyte elastase in complex with a thiazolidinedione inhibitor
Class: hydrolase
Keywords: human leukocyte elastase, human neutrophil elastase, parabolic inhibition, glycosylation, HYDROLASE
Deposited on 2017-12-01, released 2018-08-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-08, with a file datestamp of 2018-08-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil elastase
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6f5ma_
  • Chain 'B':
    Compound: Neutrophil elastase
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6f5mb_
  • Heterogens: NAG, FUC, BMA, MAN, SO4, ACT, CQH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6f5mA (A:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
    glihgiasfvrggcasglypdafapvaqfvnwidsiiq
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6f5mB (B:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
    glihgiasfvrggcasglypdafapvaqfvnwidsiiq