PDB entry 6f57

View 6f57 on RCSB PDB site
Description: crystal structure of dnmt3a-dnmt3l in complex with single cpg- containing dna
Deposited on 2017-12-01, released 2018-01-31
The last revision was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA (cytosine-5)-methyltransferase 3-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3L
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA (cytosine-5)-methyltransferase 3-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3L
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA (5'-d(*ap*gp*ap*gp*cp*gp*cp*ap*tp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'F':
    Compound: DNA (5'-d(*cp*ap*tp*gp*zp*gp*cp*tp*cp*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'G':
    Compound: DNA (5'-d(*ap*gp*ap*gp*cp*gp*cp*ap*tp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'H':
    Compound: DNA (5'-d(*cp*ap*tp*gp*zp*gp*cp*tp*cp*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: SAH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6f57A (A:)
aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdv
rsvtqkhiqewgpfdlviggspcndlsivnparkglyegtgrlffefyrllhdarpkegd
drpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplas
tvndklelqeclehgriakfskvrtittrsnsikqgkdqhfpvfmnekedilwctemerv
fgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6f57B (B:)
mfetvpvwrrqpvrvlslfedikkeltslgflesgsdpgqlkhvvdvtdtvrkdveewgp
fdlvygatpplghtcdrppswylfqfhrllqyarpkpgsprpffwmfvdnlvlnkedldv
asrflemepvtipdvhggslqnavrvwsnipairsrhwalvseeelsllaqnkqssklaa
kwptklvkncflplreyfkyfsteltssl

    Sequence, based on observed residues (ATOM records):
    >6f57B (B:)
qpvrvlslfedikkeltslgflegqlkhvvdvtdtvrkdveewgpfdlvygatpplghtc
drppswylfqfhrllqyarpkpgsprpffwmfvdnlvlnkedldvasrflemepvtipdv
qnavrvwsniptklvkncflplreyfkyfs

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6f57C (C:)
mfetvpvwrrqpvrvlslfedikkeltslgflesgsdpgqlkhvvdvtdtvrkdveewgp
fdlvygatpplghtcdrppswylfqfhrllqyarpkpgsprpffwmfvdnlvlnkedldv
asrflemepvtipdvhggslqnavrvwsnipairsrhwalvseeelsllaqnkqssklaa
kwptklvkncflplreyfkyfsteltssl

    Sequence, based on observed residues (ATOM records):
    >6f57C (C:)
tvpvwrrqpvrvlslfedikkeltslgflegqlkhvvdvtdtvrkdveewgpfdlvygat
pplghtcdrppswylfqfhrllqyarpkpgsprpffwmfvdnlvlnkedldvasrfleme
pvtiqnavrvwsniplvkncflplreyfkyf

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6f57D (D:)
aekrkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdv
rsvtqkhiqewgpfdlviggspcndlsivnparkglyegtgrlffefyrllhdarpkegd
drpffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplas
tvndklelqeclehgriakfskvrtittrsnsikqgkdqhfpvfmnekedilwctemerv
fgfpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv

    Sequence, based on observed residues (ATOM records):
    >6f57D (D:)
krkpirvlslfdgiatgllvlkdlgiqvdryiasevcedsitvgmvrhqgkimyvgdvrs
vtqkhiqewgpfdlviggspcndlsivnparkglyegtgrlffefyrllhdarpkegddr
pffwlfenvvamgvsdkrdisrflesnpvmidakevsaahraryfwgnlpgmnrplastv
ndklelqeclehgriakfskvrtittrsnsikqgkdqhfpvfmnekedilwctemervfg
fpvhytdvsnmsrlarqrllgrswsvpvirhlfaplkeyfacv

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.