PDB entry 6f3i

View 6f3i on RCSB PDB site
Description: IRAK4 IN COMPLEX WITH inhibitor
Class: signaling protein
Keywords: IRAK4, kinase, inhibitor, cancer, SIGNALING PROTEIN
Deposited on 2017-11-28, released 2018-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-23, with a file datestamp of 2018-05-18.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6f3ia_
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6f3ib_
  • Heterogens: CKN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6f3iA (A:)
mhhhhhhhenlyfqgenkslevsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfg
vvykgyvnnttvavkklaamvditteelkqqfdqeikvmakcqhenlvellgfssdgddl
clvyvympngslldrlscldgtpplswhmrckiaqgaanginflhenhhihrdiksanil
ldeaftakisdfglarasekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvll
eiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamysvasqclh
ekknkrpdikkvqqllqemtas

    Sequence, based on observed residues (ATOM records): (download) 
    >6f3iA (A:)
fhsfsfyelknvtnnfdergnkmgevvykgyvttvavkkllkqqfdqeikvmakcqhenl
vellgfsclvyvympngslldrlscldgtpplswhmrckiaqgaanginflhenhhihrd
iksanilldeaftakisdfglaravmtsrivgttaymapealrgeitpksdiysfgvvll
eiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamysvasqclh
ekknkrpdikkvqqllqemt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6f3iB (B:)
mhhhhhhhenlyfqgenkslevsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfg
vvykgyvnnttvavkklaamvditteelkqqfdqeikvmakcqhenlvellgfssdgddl
clvyvympngslldrlscldgtpplswhmrckiaqgaanginflhenhhihrdiksanil
ldeaftakisdfglarasekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvll
eiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamysvasqclh
ekknkrpdikkvqqllqemtas

    Sequence, based on observed residues (ATOM records): (download) 
    >6f3iB (B:)
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklteelkqqf
dqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrck
iaqgaanginflhenhhihrdiksanilldeaftakisdfglarasmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemt