PDB entry 6f3g

View 6f3g on RCSB PDB site
Description: IRAK4 IN COMPLEX WITH inhibitor
Class: signaling protein
Keywords: IRAK4, kinase, inhibitor, cancer, SIGNALING PROTEIN
Deposited on 2017-11-28, released 2018-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-23, with a file datestamp of 2018-05-18.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6f3ga_
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6f3gb_
  • Heterogens: CJN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6f3gA (A:)
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvditt
eelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtppl
swhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtv
mtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeei
edeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemt

    Sequence, based on observed residues (ATOM records): (download) 
    >6f3gA (A:)
rfhsfsfyelknvtnnfderpisvnkmgegvvykgyvnnttvavkklatteelkqqfdqe
ikvmakcqhenlvellgfssddlclvyvympngslldrlscldgtpplswhmrckiaqga
anginflhenhhihrdiksanilldeaftakisdfglaratvmtsrivgttaymapealr
geitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmnda
dstsveamysvasqclhekknkrpdikkvqqllqemt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6f3gB (B:)
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvditt
eelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtppl
swhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtv
mtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeei
edeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemt

    Sequence, based on observed residues (ATOM records): (download) 
    >6f3gB (B:)
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklteelkqqf
dqeikvmakcqhenlvellgfssdlclvyvympngslldrlscldgtpplswhmrckiaq
gaanginflhenhhihrdiksanilldeaftakisdfglarasvmtsrivgttaymapea
lrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmn
dadstsveamysvasqclhekknkrpdikkvqqllqemt