PDB entry 6f2y

View 6f2y on RCSB PDB site
Description: crystal structure of ectonucleotide phosphodiesterase/pyrophosphatase- 3 (npp3) in complex with ap4a
Deposited on 2017-11-27, released 2018-08-01
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
    Species: Rattus norvegicus [TaxId:10116]
    Gene: ENPP3, PDNP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P97675 (4-End)
      • variant (65)
      • engineered mutation (70)
      • variant (460-461)
  • Chain 'B':
    Compound: Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
    Species: Rattus norvegicus [TaxId:10116]
    Gene: ENPP3, PDNP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P97675 (4-End)
      • variant (65)
      • engineered mutation (70)
      • variant (460-461)
  • Heterogens: B4P, ZN, CA, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6f2yA (A:)
aetgwvteacassqepqcpegfdqppvilfsmdgfraeylqtwstllpninklktcglhs
kymravyptkafpnhytivtglypeshgiidnnmydvylnknfslssveksnpawwsgqp
iwltamyqglkaasyywpgsdvavngsfpniyrnysnsvpyesriatllqwldlpkaerp
sfytiyveepdsaghksgpvsagvikalqlvddafgmlmeglkqrnlhncvniivladhg
mdqtscdrveymtdyfpeinfymyqgpaprirtrnipqdfftfnseeivrdlscrksdqh
fkpyltpdlpkrlhyaknvridkvhlmvdrqwlayrnkgssnceggthgynnefksmeai
flahgpsfkektviepfenievynllcdllhiqpapnngshgslnhllkapfyqpshaee
lsksagcgfttplpkdslncsclalqtsgqeeqvnqrlnlnrgevsatektnlpfgrprv
iqknkdhcllyhreyvsgfgkamkmpmwssytvpkpgdtsslpptvpdclradvrvdpse
sqkcsfyladqnidhgflyppaikgnnesqydalitsnlvpmykefkkmwdyfhkvllik
yaierngvnvvsgpifdynydghfdapdeitnyvagtdvpvpthyfvvltscknkthtpd
scpgwldvlpfvvphrptnvescpenkaedlwveerfkahiarvrdvelltgldfyqekt
qpvseilqlktylptfetiigtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6f2yA (A:)
wvteacapqcpegfdqppvilfsmdgfraeylqtwstllpninklktcglhskymravyp
tkafpnhytivtglypeshgiidnnmydvylnknfslssveksnpawwsgqpiwltamyq
glkaasyywpgsdvavngsfpniyrnysnsvpyesriatllqwldlpkaerpsfytiyve
epdsaghksgpvsagvikalqlvddafgmlmeglkqrnlhncvniivladhgmdqtscdr
veymtdyfpeinfymyqgpaprirtrnipqdfftfnseeivrdlscrksdqhfkpyltpd
lpkrlhyaknvridkvhlmvdrqwlayrnknceggthgynnefksmeaiflahgpsfkek
tviepfenievynllcdllhiqpapnngshgslnhllkapfyqpshaeelsksagcgftt
plpkdslncsclalqeqvnqrlnlnrgevsatektnlpfgrprviqknkdhcllyhreyv
sgfgkamkmpmwssytvpkpgdtsslpptvpdclradvrvdpsesqkcsfyladqnidhg
flyppaikgnnesqydalitsnlvpmykefkkmwdyfhkvllikyaierngvnvvsgpif
dynydghfdapdeitnyvagtdvpvpthyfvvltscknkthtpdscpgwldvlpfvvphr
ptnvescpenkaedlwveerfkahiarvrdvelltgldfyqektqpvseilqlktylptf

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6f2yB (B:)
aetgwvteacassqepqcpegfdqppvilfsmdgfraeylqtwstllpninklktcglhs
kymravyptkafpnhytivtglypeshgiidnnmydvylnknfslssveksnpawwsgqp
iwltamyqglkaasyywpgsdvavngsfpniyrnysnsvpyesriatllqwldlpkaerp
sfytiyveepdsaghksgpvsagvikalqlvddafgmlmeglkqrnlhncvniivladhg
mdqtscdrveymtdyfpeinfymyqgpaprirtrnipqdfftfnseeivrdlscrksdqh
fkpyltpdlpkrlhyaknvridkvhlmvdrqwlayrnkgssnceggthgynnefksmeai
flahgpsfkektviepfenievynllcdllhiqpapnngshgslnhllkapfyqpshaee
lsksagcgfttplpkdslncsclalqtsgqeeqvnqrlnlnrgevsatektnlpfgrprv
iqknkdhcllyhreyvsgfgkamkmpmwssytvpkpgdtsslpptvpdclradvrvdpse
sqkcsfyladqnidhgflyppaikgnnesqydalitsnlvpmykefkkmwdyfhkvllik
yaierngvnvvsgpifdynydghfdapdeitnyvagtdvpvpthyfvvltscknkthtpd
scpgwldvlpfvvphrptnvescpenkaedlwveerfkahiarvrdvelltgldfyqekt
qpvseilqlktylptfetiigtkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6f2yB (B:)
wvteacaqcpegfdqppvilfsmdgfraeylqtwstllpninklktcglhskymravypt
kafpnhytivtglypeshgiidnnmydvylnknfslssveksnpawwsgqpiwltamyqg
lkaasyywpgsdvavngsfpniyrnysnsvpyesriatllqwldlpkaerpsfytiyvee
pdsaghksgpvsagvikalqlvddafgmlmeglkqrnlhncvniivladhgmdqtscdrv
eymtdyfpeinfymyqgpaprirtrnipqdfftfnseeivrdlscrksdqhfkpyltpdl
pkrlhyaknvridkvhlmvdrqwlayrnknceggthgynnefksmeaiflahgpsfkekt
viepfenievynllcdllhiqpapnngshgslnhllkapfyqpshaeelsksagcgfttp
lpkdslncsclalqeeqvnqrlnlnrgevsatektnlpfgrprviqknkdhcllyhreyv
sgfgkamkmpmwssytvpkpgdtsslpptvpdclradvrvdpsesqkcsfyladqnidhg
flyppaikgnnesqydalitsnlvpmykefkkmwdyfhkvllikyaierngvnvvsgpif
dynydghfdapdeitnyvagtdvpvpthyfvvltscknkthtpdscpgwldvlpfvvphr
ptnvescpekaedlwveerfkahiarvrdvelltgldfyqektqpvseilqlktylptf