PDB entry 6f25

View 6f25 on RCSB PDB site
Description: Crystal structure of human acetylcholinesterase in complex with C35.
Class: hydrolase
Keywords: Acetylcholinesterase, HYDROLASE
Deposited on 2017-11-23, released 2018-12-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-12-12, with a file datestamp of 2018-12-07.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6f25a_
  • Chain 'B':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6f25b_
  • Heterogens: NAG, FUC, SO4, CVZ, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6f25A (A:)
    daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
    fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
    sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
    envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
    rrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvd
    gdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvr
    vgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgar
    vyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfa
    rtgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat
    

    Sequence, based on observed residues (ATOM records): (download)
    >6f25A (A:)
    daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
    fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
    sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
    envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
    rrratqlahlvgcpndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdflsd
    tpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvpqv
    sdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayvf
    ehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdpn
    eprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6f25B (B:)
    daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
    fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
    sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
    envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
    rrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvd
    gdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvr
    vgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgar
    vyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfa
    rtgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat
    

    Sequence, based on observed residues (ATOM records): (download)
    >6f25B (B:)
    daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
    fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
    sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
    envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
    rrratqlahlvgcppgndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdfl
    sdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvp
    qvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyay
    vfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgd
    pneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat