PDB entry 6f00

View 6f00 on RCSB PDB site
Description: crystal structure of human trna dihydrouridine synthase (20) dsrbd e423a mutant
Deposited on 2017-11-17, released 2018-12-12
The last revision was dated 2018-12-12, with a file datestamp of 2018-12-07.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DUS2, DUS2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX74
      • engineered mutation (86)
  • Chain 'B':
    Compound: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DUS2, DUS2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX74
      • engineered mutation (86)
  • Chain 'C':
    Compound: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DUS2, DUS2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX74
      • engineered mutation (86)
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6f00A (A:)
mtseqtgepaedtsgvikmavkfdrraypaqitpkmcllewcrreklaqpvyetvqrpld
rlfssivtvaeqkyqstlwdkskklaaqaaaivclrsqglpegrlgeespslhkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6f00A (A:)
edtsgvikmavkfdrraypaqitpkmcllewcrreklaqpvyetvqrpldrlfssivtva
eqkyqstlwdkskklaaqaaaivclrsqglpegrl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6f00B (B:)
mtseqtgepaedtsgvikmavkfdrraypaqitpkmcllewcrreklaqpvyetvqrpld
rlfssivtvaeqkyqstlwdkskklaaqaaaivclrsqglpegrlgeespslhkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6f00B (B:)
paedtsgvikmavkfdrraypaqitpkmcllewcrreklaqpvyetvqrpldrlfssivt
vaeqkyqstlwdkskklaaqaaaivclrsqglpegrlge

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6f00C (C:)
mtseqtgepaedtsgvikmavkfdrraypaqitpkmcllewcrreklaqpvyetvqrpld
rlfssivtvaeqkyqstlwdkskklaaqaaaivclrsqglpegrlgeespslhkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6f00C (C:)
edtsgvikmavkfdrraypaqitpkmcllewcrreklaqpvyetvqrpldrlfssivtva
eqkyqstlwdkskklaaqaaaivclrsqglpegrl