PDB entry 6eza

View 6eza on RCSB PDB site
Description: crystal structure of human trna-dihydrouridine(20) synthase catalytic domain e294k mutant
Deposited on 2017-11-14, released 2018-09-26
The last revision was dated 2018-09-26, with a file datestamp of 2018-09-21.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DUS2, DUS2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX74 (7-End)
      • expression tag (4-6)
      • engineered mutation (287)
  • Chain 'B':
    Compound: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
    Species: Homo sapiens [TaxId:9606]
    Gene: DUS2, DUS2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NX74 (7-End)
      • expression tag (4-6)
      • engineered mutation (287)
  • Heterogens: FMN, SO4, CL, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ezaA (A:)
mhhhhhhlilapmvrvgtlpmrllaldygadivyceelidlkmiqckrvvnevlstvdfv
apddrvvfrtcereqnrvvfqmgtsdaeralavarlvendvagidvnmgcpkqystkggm
gaallsdpdkiekilstlvkgtrrpvtckirilpsledtlslvkriertgiaaiavhgrk
reerpqhpvscevikaiadtlsipvianggshdhiqqysdiedfrqataassvmvaraam
wnpsiflkeglrpleevmqkyiryavqydnhytntkyclcqmlreqlkspqgrllhaaqs
sreiceafglgafyeettqeldaqqar

    Sequence, based on observed residues (ATOM records):
    >6ezaA (A:)
hhhlilapmvrvgtlpmrllaldygadivyceelidlkmiqckrvvnevlstvdfvapdd
rvvfrtcereqnrvvfqmgtsdaeralavarlvendvagidvnmgcpkkggmgaallsdp
dkiekilstlvkgtrrpvtckirilpsledtlslvkriertgiaaiavhgrkreerpqhp
vscevikaiadtlsipvianggshdhiqqysdiedfrqataassvmvaraamwnpsiflk
eglrpleevmqkyiryavqydnhytntkyclcqmlreqlkspqgrllhaaqssreiceaf
glgafyeettqeldaqq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ezaB (B:)
mhhhhhhlilapmvrvgtlpmrllaldygadivyceelidlkmiqckrvvnevlstvdfv
apddrvvfrtcereqnrvvfqmgtsdaeralavarlvendvagidvnmgcpkqystkggm
gaallsdpdkiekilstlvkgtrrpvtckirilpsledtlslvkriertgiaaiavhgrk
reerpqhpvscevikaiadtlsipvianggshdhiqqysdiedfrqataassvmvaraam
wnpsiflkeglrpleevmqkyiryavqydnhytntkyclcqmlreqlkspqgrllhaaqs
sreiceafglgafyeettqeldaqqar

    Sequence, based on observed residues (ATOM records):
    >6ezaB (B:)
hhhlilapmvrvgtlpmrllaldygadivyceelidlkmiqckrvvnevlstvdfvapdd
rvvfrtcereqnrvvfqmgtsdaeralavarlvendvagidvnmgcpkkggmgaallsdp
dkiekilstlvkgtrrpvtckirilpsledtlslvkriertgiaaiavhgrkreerpqhp
vscevikaiadtlsipvianggshdhiqqysdiedfrqataassvmvaraamwnpsiflk
eglrpleevmqkyiryavqydnhytntkyclcqmlreqlkspqgrllhaaqssreiceaf
glgafyeettqel