PDB entry 6ez6

View 6ez6 on RCSB PDB site
Description: pi3 kinase delta in complex with methyl 5-(4-(5-((4- isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1h-indazol-6-yl)-2- methoxynicotinate
Deposited on 2017-11-14, released 2017-12-27
The last revision was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
    Species: Mus musculus [TaxId:10090]
    Gene: Pik3cd
    Database cross-references and differences (RAF-indexed):
    • Uniprot O35904
      • insertion (514)
  • Heterogens: C5Z, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ez6A (A:)
mppgvdcpmefwtkeesqsvvvdfllptgvylnfpvsrnanlstikqvlwhraqyeplfh
mlsdpeayvftcvnqtaeqqeledeqrrlcdiqpflpvlrlvareenlyfqggdrvkkli
nsqislligkglhefdslrdpevndfrtkmrqfceeaaahrqqlgwvewlqysfplqlep
sargwragllrvsnrallvnvkfegseesftfqvstkdmplalmacalrkkatvfrqplv
eqpeeyalqvngrheylygnyplchfqyicsclhsgltphltmvhsssilamrdeqsnpa
pqvqkprakpppipakkpssvslwsleqpfsieliegrkvnadermklvvqaglfhgnem
lcktvsssevnvcsepvwkqrlefdisvcdlprmarlcfalyavvekakkarstkkkskk
adcpiawanlmlfdykdqlktgerclymwpsvpdekgellnpagtvrgnpntesaaalvi
ylpevaphpvyfpalekilelgrhgergriteeeqlqlreilerrgsgelyehekdlvwk
mrhevqehfpealarlllvtkwnkhedvaqmlyllcswpelpvlsalelldfsfpdcyvg
sfaikslrkltddelfqyllqlvqvlkyesyldceltkfllgralanrkighflfwhlrs
emhvpsvalrfglimeaycrgsthhmkvlmkqgealsklkalndfvkvssqkttkpqtke
mmhmcmrqetymealshlqspldpstlleevcveqctfmdskmkplwimysseeagsagn
vgiifkngddlrqdmltlqmiqlmdvlwkqegldlrmtpygclptgdrtglievvlhsdt
ianiqlnksnmaataafnkdallnwlksknpgealdraieeftlscagycvatyvlgigd
rhsdnimiresgqlfhidfghflgnfktkfginrervpfiltydfvhviqqgktnnsekf
erfrgyceraytilrrhgllflhlfalmraaglpelscskdiqylkdslalgkteeealk
hfrvkfnealreswktkvnwlahnvskdnrq

    Sequence, based on observed residues (ATOM records):
    >6ez6A (A:)
drvkklinsqislligkglhefdslrdpevndfrtkmrqfceeaaahrqqlgwvewlqys
fplqlepsargnrallvnvkfegseesftfqvstkdmplalmacalrkkatvfrqplveq
peeyalqvngrheylygnyplchfqyicsclhsgltphltmvhsssilamrdeqsnpasl
wsleqpfsieliegrkvnadermklvvqaglfhgnemlcktvsssevnvcsepvwkqrle
fdisvcdlprmarlcfalyavvdcpiawanlmlfdykdqlktgerclymwpsvllnpagt
vrgnpntesaaalviylpevaphpvyfpalekilelgrhgergriteeeqlqlreilerg
elyehekdlvwkmrhevqehfpealarlllvtkwnkhedvaqmlyllcswpelpvlsale
lldfsfpdcyvgsfaikslrkltddelfqyllqlvqvlkyesyldceltkfllgralanr
kighflfwhlrsemhvpsvalrfglimeaycrgsthhmkvlmkqgealsklkalndfvkv
ssqkttkpqtkemmhmcmrqetymealshlqspldpstlleevcveqctfmdskmkplwi
mysseeagsagnvgiifkngddlrqdmltlqmiqlmdvlwkqegldlrmtpygclptgdr
tglievvlhsdtianiqlnksnmaataafnkdallnwlksknpgealdraieeftlscag
ycvatyvlgigdrhsdnimiresgqlfhidfghflgnrervpfiltydfvhviqqgktnn
sekferfrgyceraytilrrhgllflhlfalmraaglpelscskdiqylkdslalgktee
ealkhfrvkfnealreswktkvn