PDB entry 6eyo

View 6eyo on RCSB PDB site
Description: structure of extended ige-fc in complex with two anti-ige fabs
Deposited on 2017-11-13, released 2018-08-15
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.7 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Immunoglobulin heavy constant epsilon
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01854
      • conflict (44)
      • conflict (150)
  • Chain 'B':
    Compound: Immunoglobulin heavy constant epsilon
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01854
      • conflict (44)
      • conflict (150)
  • Chain 'H':
    Compound: 8D6 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6EYO
  • Chain 'I':
    Compound: 8D6 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6EYO
  • Chain 'L':
    Compound: 8D6 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6EYO (0-217)
  • Chain 'M':
    Compound: 8D6 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6EYO (0-End)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6eyoA (A:)
divasrdftpptvkilqsscdggghfpptiqllclvsgytpgtiqitwledgqvmdvdls
tasttqegelastqseltlsqkhwlsdrtytcqvtyqghtfedstkkcadsnprgvsayl
srpspfdlfirksptitclvvdlapskgtvqltwsrasgkpvnhstrkeekqrngtltvt
stlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapevyafatpewpgsrdkr
tlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffvfsrlevtraeweqkd
eficravheaaspsqtvqravsvnpgk

    Sequence, based on observed residues (ATOM records):
    >6eyoA (A:)
pptvkilqsscdggghfpptiqllclvsgytpgtiqitwledgqvmdvdlstasttqlas
tqseltlsqkhwlsdrtytcqvtyqtfedstkkcadsnprgvsaylsrpspfdlfirksp
titclvvdlapskgtvqltwsrasgkpvnhstrkeekqrngtltvtstlpvgtrdwiege
tyqcrvthphlpralmrsttktsgpraapevyafatpewpgsrdkrtlacliqnfmpedi
svqwlhnevqlpdarhsttqprktkffvfsrlevtraeweqkdeficravheaaspsqtv
qravsvn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6eyoB (B:)
divasrdftpptvkilqsscdggghfpptiqllclvsgytpgtiqitwledgqvmdvdls
tasttqegelastqseltlsqkhwlsdrtytcqvtyqghtfedstkkcadsnprgvsayl
srpspfdlfirksptitclvvdlapskgtvqltwsrasgkpvnhstrkeekqrngtltvt
stlpvgtrdwiegetyqcrvthphlpralmrsttktsgpraapevyafatpewpgsrdkr
tlacliqnfmpedisvqwlhnevqlpdarhsttqprktkgsgffvfsrlevtraeweqkd
eficravheaaspsqtvqravsvnpgk

    Sequence, based on observed residues (ATOM records):
    >6eyoB (B:)
pptvkilqsscdggghfpptiqllclvytpgtiqitwledgqvmdvdlstasttqastqs
eltlsqkhwlsdrtytcqvtyqghtfedstkkcadsnprgvsaylsrpspfdlfirkspt
itclvvdlapskgtvqltwsrasgkpvnhstrkeekqrngtltvtstlpvgtrdwieget
yqcrvthphlpralmrsttktsgpraapevyafatpewpgsrdkrtlacliqnfmpedis
vqwlhnevqlpdarhsttqprktkgsgffvfsrlevtraeweqkdeficravheaaspsq
tvqravsvn

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6eyoH (H:)
qvqlqqsgaelakpgasvmlsckasgytfngywmhwvkqrpgqdlewigyinpttghtey
nqkfkdkatltadessntayielssltsddsavyycarqeyrhswfaywgqgtlvtvsaa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkaepkscdktht

    Sequence, based on observed residues (ATOM records):
    >6eyoH (H:)
vqlqqsgaelakpgasvmlsckasgytfngywmhwvkqrpgqdlewigyinpttghteyn
qkfkdkatltadessntayielssltsddsavyycarqeyrhswfaywgqgtlvtvsaas
tkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvv
tvpyicnvnhkpsntkvdkkaepk

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6eyoI (I:)
qvqlqqsgaelakpgasvmlsckasgytfngywmhwvkqrpgqdlewigyinpttghtey
nqkfkdkatltadessntayielssltsddsavyycarqeyrhswfaywgqgtlvtvsaa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkaepkscdktht

    Sequence, based on observed residues (ATOM records):
    >6eyoI (I:)
vqlqqsgaelakpgasvmlsckasgytfngywmhwvkqrpgqdlewigyinpttghteyn
qkfkdkatltadessntayielssltsddsavyycarqeyrhswfaywgqgtlvtvsaas
tkgpsvfplapsstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssstqtyicnvnhkpsntkvdkka

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6eyoL (L:)
divltqspaslavslgqratisckasqsvdydgdtymnwyhqkpgqppklliyaasnlds
giparfsgsgsgtdftlnihpveeedaatyycqqtnedpwtfgggtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6eyoL (L:)
divltqspaslavslgqratisckasqsvdydgdtymnwyhqkpgqppklliyaasnlds
giparfsgsgsgtdftlnihpveeedaatyycqqtnedpwtfgggtkleikrtvaapsvf
ifppeqlksgtasvvcllnnfypreakvqwkvdnalqnsqesvteqdskdstyslsstlt
dyekhkvyacevthqglsspvtksfnrgec

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6eyoM (M:)
divltqspaslavslgqratisckasqsvdydgdtymnwyhqkpgqppklliyaasnlds
giparfsgsgsgtdftlnihpveeedaatyycqqtnedpwtfgggtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6eyoM (M:)
divltqspaslavslgqratisckasqsvdydgdtymnwyhqkpgqppklliyaasnlds
giparfsgsgsgtdftlnihpveeedaatyycqqtnedpwtfgggtkleikrtvaapsvf
ifppsdeqlsvvcllnnfypreakvdnalqsgnsqesvteqdskdstyslsstltlskkv
yacevthqglsspvtksfnrg