PDB entry 6eyc

View 6eyc on RCSB PDB site
Description: re-refinement of the mcm2-7 double hexamer using isolde
Deposited on 2017-11-11, released 2018-06-20
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 3.8 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '2':
    Compound: DNA replication licensing factor mcm2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: MCM2, YBL023C, YBL0438
    Database cross-references and differences (RAF-indexed):
  • Chain '3':
    Compound: DNA replication licensing factor MCM3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: MCM3, YEL032W, SYGP-ORF23
    Database cross-references and differences (RAF-indexed):
  • Chain '4':
    Compound: DNA replication licensing factor MCM4
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: MCM4, CDC54, HCD21, YPR019W, YP9531.13
    Database cross-references and differences (RAF-indexed):
  • Chain '5':
    Compound: Minichromosome maintenance protein 5
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: MCM5, CDC46, YLR274W, L9328.1
    Database cross-references and differences (RAF-indexed):
  • Chain '6':
    Compound: DNA replication licensing factor MCM6
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: MCM6, YGL201C
    Database cross-references and differences (RAF-indexed):
  • Chain '7':
    Compound: DNA replication licensing factor MCM7
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: MCM7, CDC47, YBR202W, YBR1441
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, ADP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain '2':
    Sequence, based on SEQRES records:
    >6eyc2 (2:)
msdnrrrrreeddsdsenelppsspqqhfrggmnpvsspigspdminpegddnevddvpd
ideveeqmnevdlmddnmyedyaadhnrdrydpdqvddreqqelslserrridaqlnerd
rllrnvayiddedeeqegaaqldemglpvqrrrrrrqyedlensdddllsdmdidplree
ltleslsnvkansysewitqpnvsrtiarelksflleytdetgrsvygarirtlgemnse
slevnyrhlaeskailalflakcpeemlkifdlvameatelhypdyarihseihvrisdf
ptiyslrelresnlsslvrvtgvvtrrtgvfpqlkyvkfnclkcgsilgpffqdsneeir
isfctnckskgpfrvngektvyrnyqrvtlqeapgtvppgrlprhrevilladlvdvskp
geevevtgiyknnydgnlnakngfpvfatiieansikrregntanegeegldvfswteee
erefrkisrdrgiidkiissmapsiyghrdiktavacslfggvpknvngkhsirgdinvl
llgdpgtaksqilkyvektahravfatgqgasavgltasvrkdpitkewtleggalvlad
kgvclidefdkmndqdrtsiheameqqsisiskagivttlqarcsiiaaanpnggrynst
lplaqnvsltepilsrfdilcvvrdlvdeeaderlatfvvdshvrshpendedregeelk
nngesaieqgedeineqlnarqrrlqrqrkkeeeispipqellmkyihyartkiypklhq
mdmdkvsrvyadlrresistgsfpitvrhlesilriaesfakmrlsefvssydldraikv
vvdsfvdaqkvsvrrqlrrsfaiytlgh

    Sequence, based on observed residues (ATOM records):
    >6eyc2 (2:)
pnvsrtiarelksflleytdetgrsvygarirtlgemnseslevnyrhlaeskailalfl
akcpeemlkifdlvameatelhypdyarihseihvrisdfptiyslrelresnlsslvrv
tgvvtrrtgvfpqlkyvkfnclkcgsilgpffqdsneeirisfctnckskgpfrvngekt
vyrnyqrvtlqeapgtvppgrlprhrevilladlvdvskpgeevevtgiyknnydgnlna
kngfpvfatiieansikrrevfswteeeerefrkisrdrgiidkiissmapsiyghrdik
tavacslfggvpknvngkhsirgdinvlllgdpgtaksqilkyvektahravfatgqgas
avgltasvrkdpitkewtleggalvladkgvclidefdkmndqdrtsiheameqqsisis
kagivttlqarcsiiaaanpnggrynstlplaqnvsltepilsrfdilcvvrdlvdeead
erlatfvvdshvrsspipqellmkyihyartkiypklhqmdmdkvsrvyadlrresistg
sfpitvrhlesilriaesfakmrlsefvssydldraikvvvdsfvdaqkvsvrrqlrrsf
aiy

  • Chain '3':
    Sequence, based on SEQRES records:
    >6eyc3 (3:)
megstgfdgdattffapdavfgdrvrrfqefldtftsyrdsvrsiqvynsnnaanynddq
ddaderdllgdddgddlekekkaasstslnilphriiislddlrefdrsfwsgilvepay
fippaekaltdladsmddvphpnasavssrhpwklsfkgsfgahalsprtltaqhlnklv
svegivtktslvrpklirsvhyaaktgrfhyrdytdatttlttriptpaiyptedtegnk
ltteygystfidhqritvqempemapagqlprsidvildddlvdktkpgdrvnvvgvfks
lgaggmnqsnsntligfktlilgntvyplharstgvaarqmltdfdirninklskkkdif
dilsqslapsiyghdhikkaillmlmggveknlengshlrgdinilmvgdpstaksqllr
fvlntaslaiattgrgssgvgltaavttdretgerrleagamvladrgvvcidefdkmtd
vdrvaihevmeqqtvtiakagihttlnarcsviaaanpvfgqydvnrdphqnialpdsll
srfdllfvvtddineirdrsisehvlrthrylppgylegepvrerlnlslavgedadinp
eehsnsgagvenegeddedhvfekfnpllqagaklaknkgnyngteipklvtipflrkyv
qyakervipqltqeainvivknytdlrnddntkkspitartletlirlatahakvrlskt
vnkvdakvaanllrfallgedigndideeeseyeealskrspqkspkkrqrvrqpasnsg
spikstprrstassvnatpssarrilrfqddeqnageddndimsplpadeeaelqrrlql
glrvsprrrehlhapeegssgpltevgtprlpnvssagqddeqqqsvisfdnvepgtist
grlslisgiiarlmqteifeeesypvaslferineelpeeekfsaqeylaglkimsdrnn
lmvaddkvwrv

    Sequence, based on observed residues (ATOM records):
    >6eyc3 (3:)
tffapdavfgdrvrrfqefldtftsyrdsvrsiqvynsnnaanynddqdilphriiisld
dlrefdrsfwsgilvepayfippaekaltdladsmddvphhpwklsfkgsfgahalsprt
ltaqhlnklvsvegivtktslvrpklirsvhyaaktgrfhyrdytdatttlttriptpai
yptedtegnkltteygystfidhqritvqempemapagqlprsidvildddlvdktkpgd
rvnvvgvfkslgaggmnqsnligfktlilgntvyplharstgvaarqmltdfdirninkl
skkkdifdilsqslapsiyghdhikkaillmlmggveknlengshlrgdinilmvgdpst
aksqllrfvlntaslaiattgrgssgvgltaavttdretgerrleagamvladrgvvcid
efdkmtdvdrvaihevmeqqtvtiakagihttlnarcsviaaanpvfgqydvnrdphqni
alpdsllsrfdllfvvtddineirdrsisehvlrthrvtipflrkyvqyakervipqltq
eainvivknytdlrnddntkkspitartletlirlatahakvrlsktvnkvdakvaanll
rfall

  • Chain '4':
    Sequence, based on SEQRES records:
    >6eyc4 (4:)
msqqsssptkednnssspvvpnpdsvppqlsspalfysssssqgdiygrnnsqnlsqgeg
niraaigssplnfpsssqrqnsdvfqsqgrqgrirssasasgrsryhsdlrsdralptss
sslgrngqnrvhmrrndihtsdlssprrivdfdtrsgvntldtssssappseaseplrii
wgtnvsiqecttnfrnflmsfkykfrkildereefinnttdeelyyikqlnemrelgtsn
lnldarnllaykqtedlyhqllnypqevisimdqtikdcmvslivdnnldydldeietkf
ykvrpynvgsckgmrelnpndidklinlkglvlrstpvipdmkvaffkcnvcdhtmavei
drgviqeparceridcnepnsmslihnrcsfadkqviklqetpdfvpdgqtphsislcvy
delvdscragdrievtgtfrsipiransrqrvlkslyktyvdvvhvkkvsdkrldvdtst
ieqelmqnkvdhneveevrqitdqdlakirevaaredlysllarsiapsiyeledvkkgi
llqlfggtnktftkggryrgdinillcgdpstsksqilqyvhkitprgvytsgkgssavg
ltayitrdvdtkqlvlesgalvlsdggvccidefdkmsdstrsvlhevmeqqtisiakag
iittlnarssilasanpigsrynpnlpvtenidlpppllsrfdlvylvldkvdekndrel
akhltnlyledkpehisqddvlpvefltmyisyakehihpiiteaaktelvrayvgmrkm
gddsrsdekritattrqlesmirlaeahakmklknvveledvqeavrlirsaikdyatdp
ktgkidmnlvqtgksviqrklqedlsreimnvlkdqasdsmsfnelikqinehsqdrves
sdiqealsrlqqedkvivlgegvrrsvrlnnrv

    Sequence, based on observed residues (ATOM records):
    >6eyc4 (4:)
lriiwgtnvsiqecttnfrnflmsfkykfrkilderdeelyyikqlnemrelgtsnlnld
arnllaykqtedlyhqllnypqevisimdqtikdcmvslivdnnldydldeietkfykvr
pynvgsckgmrelnpndidklinlkglvlrstpvipdmkvaffkcnvcdhtmaveidrgv
iqeparceridcnepnsmslihnrcsfadkqviklqetpdfvpdgqtphsislcvydelv
dscragdrievtgtfrsipiransrqrvlkslyktyvdvvhvkkvsdkrldvdtstieqe
lmqnkvdhneveevrqitdqdlakirevaaredlysllarsiapsiyeledvkkgillql
fggtnktftkggryrgdinillcgdpstsksqilqyvhkitprgvytsgkgssavgltay
itrdvdtkqlvlesgalvlsdggvccidefdkmsdstrsvlhevmeqqtisiakagiitt
lnarssilasanpigsrynpnlpvtenidlpppllsrfdlvylvldkvdekndrelakhl
tnlyledkpehisqddvlpvefltmyisyakehihpiiteaaktelvrayvgmrkattrq
lesmirlaeahakmklknvveledvqeavrlirsaikdyat

  • Chain '5':
    Sequence, based on SEQRES records:
    >6eyc5 (5:)
msfdrpeiysapvlqgespndddnteiiksfknfilefrldsqfiyrdqlrnnilvknys
ltvnmehligynediykklsdepsdiiplfetaitqvakrisilsraqsannndkdpent
smdtdslllnslptfqlilnsnanqiplrdldsehvskivrlsgiiistsvlssratyls
imcrncrhttsitinnfnsitgntvslprsclstiesessmanesnigdestkkncgpdp
yiiihesskfidqqflklqeipelvpvgemprnltmtcdryltnkvipgtrvtivgiysi
ynskngagsgrsgggnggsgvairtpyikilgiqsdvetssiwnsvtmfteeeeeeflql
srnpklyeiltnsiapsifgnedikkaivcllmggskkilpdgmrlrgdinvlllgdpgt
aksqllkfvekvspiavytsgkgssaagltasvqrdpmtrefyleggamvladggvvcid
efdkmrdedrvaiheameqqtisiakagittvlnsrtsvlaaanpiygryddlkspgdni
dfqttilsrfdmifivkddhneerdisianhvinihtgnanamqnqqeengseisiekmk
ryitycrlkcaprlspqaaeklssnfvtirkqllinelesterssipitirqleaiirit
eslaklelspiaqerhvdeairlfqastmdaasqdpigglnqasgtslseirrfeqelkr
rlpigwstsyqtlrrefvdthrfsqlaldkalyalekhetiqlrhqgqniyrsgv

    Sequence, based on observed residues (ATOM records):
    >6eyc5 (5:)
sfdrpeiysapvlqgespndddnteiiksfknfilefrldsqfiyrdqlrnnilvknysl
tvnmehligynediykklsdepsdiiplfetaitqvakrisilsraqsanslptfqliln
snanqiplrdldsehvskivrlsgiiistsvlssratylsimcrncrhttsitinnfntg
ntvslprscncgpdpyiiihesskfidqqflklqeipelvpvgemprnltmtcdryltnk
vipgtrvtivgiysiynskngsgvairtpyikilgiqsdvetssiwnsvtmfteeeeeef
lqlsrnpklyeiltnsiapsifgnedikkaivcllmggskkilpdgmrlrgdinvlllgd
pgtaksqllkfvekvspiavytsgkgssaagltasvqrdpmtrefyleggamvladggvv
cidefdkmrdedrvaiheameqqtisiakagittvlnsrtsvlaaanpiygryddlkspg
dnidfqttilsrfdmifivkddhneerdisianhvinihtgnanamqnqqeengseisie
kmkryitycrlkcaprlspqaaeklssnfvtirkqllinelesterpitirqleaiirit
eslaklelspiaqerhvdeairlfqastmdaas

  • Chain '6':
    Sequence, based on SEQRES records:
    >6eyc6 (6:)
msspfpadtpssnrpsnsspppssigagfgsssgldsqigsrlhfpsssqphvsnsqtgp
fvndstqfssqrlqtdgsatndmegneparsfksralnhvkkvddvtgekvreafeqfle
dfsvqstdtgevekvyraqiefmkiydlntiyidyqhlsmrengalamaiseqyyrflpf
lqkglrrvvrkyapellntsdslkrsegdegqadedeqqdddmngsslprdsgssaapgn
gtsamatrsittstspeqtervfqisffnlptvhrirdirsekigsllsisgtvtrtsev
rpelykasftcdmcraivdnveqsfkyteptfcpnpscenrafwtlnvtrsrfldwqkvr
iqenaneiptgsmprtldvilrgdsverakpgdrckftgveivvpdvtqlglpgvkpsst
ldtrgisktteglnsgvtglrslgvrdltykisflachvisigsnigasspdansnnret
elqmaanlqannvyqdnerdqevflnslssdeinelkemvkdehiydklvrsiapavfgh
eavkkgillqmlggvhkstvegiklrgdinicvvgdpstsksqflkyvvgfaprsvytsg
kassaagltaavvrdeeggdytieagalmladngiccidefdkmdisdqvaiheameqqt
isiakagihatlnartsilaaanpvggrynrklslrgnlnmtapimsrfdlffvilddcn
ekidtelashivdlhmkrdeaieppfsaeqlrryikyartfkpiltkearsylvekykel
rkddaqgfsrssyritvrqlesmirlseaiarancvdeitpsfiaeaydllrqsiirvdv
ddvemdeefdniesqshaasgnnddnddgtgsgvitseppadieegqseatarpgtsekk
kttvtydkyvsmmnmivrkiaevdregaeeltavdivdwyllqkendlgslaeyweerrl
afkvikrlvkdrilmeihgtrhnlrdleneenennktvyvihpncevldqlepqdss

    Sequence, based on observed residues (ATOM records):
    >6eyc6 (6:)
vddvtgekvreafeqfledfsvqstdtgevekvyraqiefmkiydlntiyidyqhlsmre
ngalamaiseqyyrflpflqkglrrvvrkyapervfqisffnlptvhrirdirsekigsl
lsisgtvtrtsevrpelykasftcdmcraivdnveqsfkyteptfcpnpscenrafwtln
vtrsrfldwqkvriqenaneiptgsmprtldvilrgdsverakpgdrckftgveivvpdv
tqlglpgvkpsstldtrgisktrslgvrdltykisflachvisigsdeinelkemvkdeh
iydklvrsiapavfgheavkkgillqmlggvhkstvegiklrgdinicvvgdpstsksqf
lkyvvgfaprsvytsgkassaagltaavvrdeeggdytieagalmladngiccidefdkm
disdqvaiheameqqtisiakagihatlnartsilaaanpvggrynrklslrgnlnmtap
imsrfdlffvilddcnekidtelashivdlhmkrdeaieppfsaeqlrryikyartfkpi
ltkearsylvekykelrkddaqgfsrssyritvrqlesmirlseaiarancvdeitpsfi
aeaydllrqsiirvdv

  • Chain '7':
    Sequence, based on SEQRES records:
    >6eyc7 (7:)
msaalpsiqlpvdynnlfneitdflvtfkqdtlssdatrnenedenldaenieqhllekg
pkymamlqkvanrelnsviidlddilqyqnekflqgtqaddlvsaiqqnanhftelfcra
idnnmplptkeidykddvldvilnqrrlrnermlsdrtneirsenlmdttmdppssmnda
lrevvedetelfppnltrryflyfkplsqncarryrkkaisskplsvrqikgdflgqlit
vrgiitrvsdvkpaveviaytcdqcgyevfqevnsrtftplsectseecsqnqtkgqlfm
straskfsafqeckiqelsqqvpvghiprslnihvngtlvrslspgdivdvtgiflpapy
tgfkalkaglltetyleaqfvrqhkkkfasfsltsdveervmelitsgdvynrlaksiap
eiygnldvkkalllllvggvdkrvgdgmkirgdinvclmgdpgvaksqllkaickisprg
vyttgkgssgvgltaavmkdpvtdemileggalvladngiccidefdkmdesdrtaihev
meqqtisiskaginttlnartsilaaanplygrynprlspldninlpaallsrfdilflm
ldipsrdddeklaehvtyvhmhnkqpdldftpvepskmreyiayaktkrpvmseavndyv
vqayirlrqdskremdskfsfgqatprtllgiirlsqalaklrladmvdiddveealrlv
rvskeslyqetnkskedespttkiftiikkmlqetgkntlsyenivktvrlrgftmlqls
nciqeysylnvwhlinegntlkfvddgtmdtdqedslvstpklapqttasanvsaqdsdi
dlqda

    Sequence, based on observed residues (ATOM records):
    >6eyc7 (7:)
msaalpsiqlpvdynnlfneitdflvtfkqdkgpkymamlqkvanrelnsviidlddilq
yqnekflqgtqaddlvsaiqqnanhftelfcraidnnmplptkeidykddvldvilnqrr
lrnermlsdrtneirsenlmndalrevvedetelfppnltrryflyfkplsqncarryri
sskplsvrqikgdflgqlitvrgiitrvsdvkpaveviaytcdqcgyevfqevnsrtftp
lsectseecsqnqtkgqlfmstraskfsafqeckiqelsqqvpvghiprslnihvngtlv
rslspgdivdvtgiflpapytgfkalkaglltetyleaqfvrqhkkkfasfsltsdveer
vmelitsgdvynrlaksiapeiygnldvkkalllllvggvdkrvgdgmkirgdinvclmg
dpgvaksqllkaickisprgvyttgkgssgvgltaavmkdpvtdemileggalvladngi
ccidefdkmdesdrtaihevmeqqtisiskaginttlnartsilaaanplygrynprlsp
ldninlpaallsrfdilflmldipsrdddeklaehvtyvhmhnkqpdldftpvepskmre
yiayaktkrpvmseavndyvvqayirlrqdskremdskfsfgqatprtllgiirlsqala
klrladmvdiddveealrlvrvskeslyq