PDB entry 6ex8

View 6ex8 on RCSB PDB site
Description: Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor
Class: hydrolase
Keywords: Cysteine Protease, Papain-like Protease, Cathepsin L-like Protease, Endopeptidase, Hydrolase
Deposited on 2017-11-07, released 2018-04-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-09, with a file datestamp of 2018-05-04.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cysteine protease
    Species: Trypanosoma brucei rhodesiense [TaxId:31286]
    Gene: rhodesain
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95PM0 (0-216)
      • engineered mutation (171)
    Domains in SCOPe 2.08: d6ex8a_
  • Chain 'B':
    Compound: Cysteine protease
    Species: Trypanosoma brucei rhodesiense [TaxId:31286]
    Gene: rhodesain
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95PM0 (0-216)
      • engineered mutation (171)
    Domains in SCOPe 2.08: d6ex8b_
  • Heterogens: C2K, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ex8A (A:)
apaavdwrekgavtpvkdqgqcgscwafstigniegqwqvagnplvslseqmlvscdtid
fgcggglmdnafnwivnsnggnvfteasypyvsgngeqpqcqmngheigaaitdhvdlpq
dedaiaaylaengplaiavdatsfmdynggiltsctseqldhgvllvgyndasnppywii
knswsnmwgedgyiriekgtnqclmnqavssavvggp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ex8B (B:)
apaavdwrekgavtpvkdqgqcgscwafstigniegqwqvagnplvslseqmlvscdtid
fgcggglmdnafnwivnsnggnvfteasypyvsgngeqpqcqmngheigaaitdhvdlpq
dedaiaaylaengplaiavdatsfmdynggiltsctseqldhgvllvgyndasnppywii
knswsnmwgedgyiriekgtnqclmnqavssavvggp