PDB entry 6ewx

View 6ewx on RCSB PDB site
Description: structure of pragmin pseudo-kinase reveals a dimerization mechanism to regulate protein tyrosine phosphorylation and nuclear transcription
Deposited on 2017-11-06, released 2018-01-31
The last revision was dated 2018-04-18, with a file datestamp of 2018-04-13.
Experiment type: XRAY
Resolution: 2.77 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: PEAK1-related kinase-activating pseudokinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Prag1, Pragmin, RGD1311793_predicted, rCG_43329
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: PEAK1-related kinase-activating pseudokinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Prag1, Pragmin, RGD1311793_predicted, rCG_43329
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ewxA (A:)
mgsshhhhhhssglvprgshmssqlqlhsllssisskegtyaklgglytqslarlvtkce
dlfmgglktelrfdenswslfklicnkpccdsgdaiyygatcskdpdsiyavkicktpep
ksasycspsvpvhfniqqdcghfvasvpssmlafpdtsskdpapaapshtpaqeqdcvvv
itrevphqtasdfvrdsvashraepevyerrvcflllqlcnglehlkehgiihrdlclen
lllvhcnpqsspgpsanpsvptttsrcpsaapaattacqggpgekhlprliisnflkakq
kpggttnlqqkksqarlapeivsasqyrkfdefqtgiliyellhqpnpfevraqlrerdy
rredlpplptlslyspglqqlahllleadpikririgeakrvlqcllwgprrelveqpcp
seevlcntlhnwidmkralmmmkfaekaverrrgveledwlccqylasaepgallqslkl
lqll

    Sequence, based on observed residues (ATOM records):
    >6ewxA (A:)
llssisskegtyaklgglytqslarlvtkcedlfmgelrfdenswslfklicpccdsgda
iyygatcskdpdsiyavkicktpvpvhfniqqdcghfvasvpssmlqeqdcvvvitrevp
hqtasdfvrdsvashraepevyerrvcflllqlcnglehlkehgiihrdlclenlllvhc
nphlprliisnflkakqkqarlapeivsasqyrkfdefqtgiliyellhqpnpferredl
pplptlslyspglqqlahllleadpikririgeakrvlqcllwgprrelveqpcpseevl
cntlhnwidmkralmmmkfaekaverrrgveledwlccqylasaepgallqslkllqll

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ewxB (B:)
mgsshhhhhhssglvprgshmssqlqlhsllssisskegtyaklgglytqslarlvtkce
dlfmgglktelrfdenswslfklicnkpccdsgdaiyygatcskdpdsiyavkicktpep
ksasycspsvpvhfniqqdcghfvasvpssmlafpdtsskdpapaapshtpaqeqdcvvv
itrevphqtasdfvrdsvashraepevyerrvcflllqlcnglehlkehgiihrdlclen
lllvhcnpqsspgpsanpsvptttsrcpsaapaattacqggpgekhlprliisnflkakq
kpggttnlqqkksqarlapeivsasqyrkfdefqtgiliyellhqpnpfevraqlrerdy
rredlpplptlslyspglqqlahllleadpikririgeakrvlqcllwgprrelveqpcp
seevlcntlhnwidmkralmmmkfaekaverrrgveledwlccqylasaepgallqslkl
lqll

    Sequence, based on observed residues (ATOM records):
    >6ewxB (B:)
lqlhsllssisskegtyaklgglytqslarlvtkcedlfmgglktelfklicnkpccdsg
daiyygatcskdpdsiyavkickcspsvpvhfniqqdcghfvasvpscvvvitrevphqt
asdfvrdsvashraepevyerrvcflllqlcnglehlkehgiihrdlclenlllvhckhl
prliisnflkakqkpgksqarlapeivsasqyrkfdefqtgiliyellhqpnpferedlp
plptlslyspglqqlahllleadpikririgeakrvlqcllwgprrelveqpcpseevlc
ntlhnwidmkralmmmkfaekaverrrgveledwlccqylasaepgallqslkllqll