PDB entry 6ewa

View 6ewa on RCSB PDB site
Description: crystal structure of hla-a2 in complex with lilrb1
Deposited on 2017-11-03, released 2018-11-07
The last revision was dated 2019-01-16, with a file datestamp of 2019-01-11.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Polyprotein
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: lir-1
    Species: Homo sapiens [TaxId:9606]
    Gene: LILRB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Polyprotein
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: lir-1
    Species: Homo sapiens [TaxId:9606]
    Gene: LILRB1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6ewaA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6ewaB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6ewaC (C:)
ilkepvhgv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ewaD (D:)
pkptlwaepgsvitqgspvtlrcqggqetqeyrlyrekktapwitripqelvkkgqfpip
sitwehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtlqcd
sqvafdgfilckegedehpqclnsqphargssraifsvgpvspsrrwwyrcyaydsnspy
ewslpsdllellvlg

    Sequence, based on observed residues (ATOM records):
    >6ewaD (D:)
pkptlwaepgsvitqgspvtlrcqyrlyrekktapwitripfpipsitwehagryrcyys
essdplelvvtgayikptlsaqpspvvnsggnvtlqcdsqvafdgfilckegpqclnsqp
hargssraifsvgpvspsrrwwyrcyaydsnspyewslpsdllellvlg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ewaE (E:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep

    Sequence, based on observed residues (ATOM records):
    >6ewaE (E:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrw

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >6ewaF (F:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >6ewaG (G:)
ilkepvhgv

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ewaH (H:)
pkptlwaepgsvitqgspvtlrcqggqetqeyrlyrekktapwitripqelvkkgqfpip
sitwehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtlqcd
sqvafdgfilckegedehpqclnsqphargssraifsvgpvspsrrwwyrcyaydsnspy
ewslpsdllellvlg

    Sequence, based on observed residues (ATOM records):
    >6ewaH (H:)
pkptlwaepgsvitqgspvtlrcqgqeyrlyrekktapwitripqelvkkgqfpipsitw
ehagryrcyygsdtagrsessdplelvvtgayikptlsaqpspvvnsggnvtlqcdsqva
fdgfilckegepqclnsqphargssraifsvgpvspsrrwwyrcyaydsnspyewslpsd
llellvlg