PDB entry 6euv

View 6euv on RCSB PDB site
Description: structure of the midlink and cap-binding domains of influenza a polymerase pb2 subunit with a bound azaindole cap-binding inhibitor (vx-787)
Deposited on 2017-10-31, released 2017-12-13
The last revision was dated 2018-02-07, with a file datestamp of 2018-02-02.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus (strain A/Victoria/3/1975 H3N2) [TaxId:392809]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus (strain A/Victoria/3/1975 H3N2) [TaxId:392809]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus (strain A/Victoria/3/1975 H3N2) [TaxId:392809]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus (strain A/Victoria/3/1975 H3N2) [TaxId:392809]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 21G, NI, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6euvA (A:)
ggevrnddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeq
avdickaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmv
gkratailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranq
rlnpmhqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgvd
eysstervvvsidrflrvrdqrgnvllspeevsethgterltitysssmm

    Sequence, based on observed residues (ATOM records):
    >6euvA (A:)
nddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeqavdic
kaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmvgkrat
ailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranqrlnpm
hqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgvstervv
vsidrflrvrdqrgnvllspeevsethgterltitys

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6euvC (C:)
ggevrnddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeq
avdickaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmv
gkratailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranq
rlnpmhqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgvd
eysstervvvsidrflrvrdqrgnvllspeevsethgterltitysssmm

    Sequence, based on observed residues (ATOM records):
    >6euvC (C:)
evrnddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeqav
dickaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmvgk
ratailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranqrl
npmhqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgvsst
ervvvsidrflrvrdqrgnvllspeevsethgterltitysss

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6euvF (F:)
ggevrnddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeq
avdickaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmv
gkratailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranq
rlnpmhqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgvd
eysstervvvsidrflrvrdqrgnvllspeevsethgterltitysssmm

    Sequence, based on observed residues (ATOM records):
    >6euvF (F:)
nddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeqavdic
kaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmvgkrat
ailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranqrlnpm
hqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgtervvvs
idrflrvrdqrgnvllspeevsethgterltitys

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6euvI (I:)
ggevrnddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeq
avdickaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmv
gkratailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranq
rlnpmhqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgvd
eysstervvvsidrflrvrdqrgnvllspeevsethgterltitysssmm

    Sequence, based on observed residues (ATOM records):
    >6euvI (I:)
nddidqsliiaarnivrrasvsadplasllemchstqiggtrmvdilrqnpteeqavdic
kaamglrisssfsfggftfkrtsgssikreeevltgnlqtlkirvhegyeeftmvgkrat
ailrkatrrlvqlivsgrdeqsiaeaiivamvfsqedcmikavrgdlnfvnranqrlnpm
hqllrhfqkdakvlfqnwgiehidnvmgmvgvlpdmtpstemsmrgirvskmgstervvv
sidrflrvrdqrgnvllspeevsethgterltitysss