PDB entry 6ety

View 6ety on RCSB PDB site
Description: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor JHU3371
Class: hydrolase
Keywords: glutamate carboxypeptidase II (GCPII); NAALADase; prostate-specific membrane antigen; phosphoramidate, HYDROLASE
Deposited on 2017-10-27, released 2018-11-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutamate carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: FOLH1, FOLH, NAALAD1, PSM, PSMA, GIG27
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6etya1, d6etya2, d6etya3
  • Heterogens: BXK, NAG, ZN, CA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6etyA (A:)
kssneatnitpkhnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkef
gldsvelahydvllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsa
fspqgmpegdlvyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagak
gvilysdpadyfapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgi
aeavglpsipvhpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvk
mhihstnevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfg
tlkkegwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlr
vdctplmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfev
ffqrlgiasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggm
vfelansivlpfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteia
skfserlqdfdksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyage
sfpgiydalfdieskvdpskawgevkrqiyvaaftvqaaaetlseva

    Sequence, based on observed residues (ATOM records): (download) 
    >6etyA (A:)
khnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahyd
vllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdl
vyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpady
fapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipv
hpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvkmhihstnevtr
iynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkkegwrprr
tilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctplmyslv
hnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrlgiasgr
arytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivlp
fdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdfd
ksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalfd
ieskvdpskawgevkrqiyvaaftvqaaaetlseva