PDB entry 6etg

View 6etg on RCSB PDB site
Description: Crystal structure of KDM4D with tetrazolhydrazide compound 6
Class: gene regulation
Keywords: KDM4D, ligand binding, Tetrazolylhydrazide, tetrazole, inhibitor design, cancer, epigenetics, GENE REGULATION
Deposited on 2017-10-26, released 2019-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 1.28 Å
R-factor: N/A
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific demethylase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: KDM4D, JHDM3D, JMJD2D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6etga_
  • Heterogens: ZN, NI, EDO, SO4, BWT, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6etgA (A:)
metmkskancaqnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkar
etydniseiliatplqqvasgragvftqyhkkkkamtvgeyrhlanskkyqtpphqnfed
lerkywknriynspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpyl
yfgmwkttfawhtedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcga
flrhkvalisptvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprw
idygkmasqcscgearvtfsmdafvrilqperydlwkrgqdr

    Sequence, based on observed residues (ATOM records): (download) 
    >6etgA (A:)
aqnpncnimifhptkeefndfdkyiaymesqgahraglakiippkewkaretydniseil
iatplqqvasgragvftqyhkkkkamtvgeyrhlanskkyqtpphqnfedlerkywknri
ynspiygadisgslfdentkqwnlghlgtiqdllekecgvviegvntpylyfgmwkttfa
whtedmdlysinylhlgepktwyvvppehgqrlerlarelfpgssrgcgaflrhkvalis
ptvlkengipfnritqeagefmvtfpygyhagfnhgfncaeainfatprwidygkmasqc
scgearvtfsmdafvrilqperydlwkrgqd