PDB entry 6et9

View 6et9 on RCSB PDB site
Description: structure of the acetoacetyl-coa-thiolase/hmg-coa-synthase complex from methanothermococcus thermolithotrophicus at 2.75 a
Deposited on 2017-10-25, released 2018-03-14
The last revision was dated 2018-04-11, with a file datestamp of 2018-04-06.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase thiolase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (0-391)
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase thiolase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (0-391)
  • Chain 'C':
    Compound: Acetyl-CoA acetyltransferase thiolase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (0-391)
  • Chain 'D':
    Compound: Acetyl-CoA acetyltransferase thiolase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (0-391)
  • Chain 'E':
    Compound: Pfam DUF35
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9
  • Chain 'F':
    Compound: Pfam DUF35
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9
  • Chain 'G':
    Compound: Pfam DUF35
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9
  • Chain 'H':
    Compound: Pfam DUF35
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9
  • Chain 'I':
    Compound: Hydroxymethylglutaryl-CoA synthase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (Start-348)
  • Chain 'J':
    Compound: Hydroxymethylglutaryl-CoA synthase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (Start-348)
  • Chain 'K':
    Compound: Hydroxymethylglutaryl-CoA synthase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (Start-348)
  • Chain 'L':
    Compound: Hydroxymethylglutaryl-CoA synthase
    Species: Methanothermococcus thermolithotrophicus [TaxId:2186]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ET9 (Start-348)
  • Heterogens: NA, TRS, K, CL, MG, GOL, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6et9A (A:)
mrdvaiigygqtkfgelwedsfrdliveagvkaikdanvdggdidamyignmsgglfvgq
ehiasliadhaglnpvpctrveaacasgslalrsavlsvasghhdvvlaggvekmtdved
ataaiasasdqeweaffgatfpslyammarrymyqygltieelsmwsviahenatknkya
qfgfkttleqvmnaspvadpltlmhcspvsdgasalivcdadkaeefapkdeiiyikast
qasdtialhdredmttlnaakvasekayklakiapekidvaevhdcfainglilvedlgf
ckkgdagkvidegkiridyddfvtvnpsgglkaaghalgatgirqvgelywqlkqdkeck
drqatikngygiaanvggtggtvcvhllsdkr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6et9B (B:)
mrdvaiigygqtkfgelwedsfrdliveagvkaikdanvdggdidamyignmsgglfvgq
ehiasliadhaglnpvpctrveaacasgslalrsavlsvasghhdvvlaggvekmtdved
ataaiasasdqeweaffgatfpslyammarrymyqygltieelsmwsviahenatknkya
qfgfkttleqvmnaspvadpltlmhcspvsdgasalivcdadkaeefapkdeiiyikast
qasdtialhdredmttlnaakvasekayklakiapekidvaevhdcfainglilvedlgf
ckkgdagkvidegkiridyddfvtvnpsgglkaaghalgatgirqvgelywqlkqdkeck
drqatikngygiaanvggtggtvcvhllsdkr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6et9C (C:)
mrdvaiigygqtkfgelwedsfrdliveagvkaikdanvdggdidamyignmsgglfvgq
ehiasliadhaglnpvpctrveaacasgslalrsavlsvasghhdvvlaggvekmtdved
ataaiasasdqeweaffgatfpslyammarrymyqygltieelsmwsviahenatknkya
qfgfkttleqvmnaspvadpltlmhcspvsdgasalivcdadkaeefapkdeiiyikast
qasdtialhdredmttlnaakvasekayklakiapekidvaevhdcfainglilvedlgf
ckkgdagkvidegkiridyddfvtvnpsgglkaaghalgatgirqvgelywqlkqdkeck
drqatikngygiaanvggtggtvcvhllsdkr

    Sequence, based on observed residues (ATOM records):
    >6et9C (C:)
mrdvaiigygqtkfgelwedsfrdliveagvkaikdanvdggdidamyignmsgglfvgq
ehiasliadhaglnpvpctrveaacasgslalrsavlsvasghhdvvlaggvekmtdved
ataaiasasdqeweaffgatfpslyammarrymyqygltieelsmwsviahenatknkya
qfgfkttleqvmnaspvadpltlmhcspvsdgasalivcdadkaeefapkdeiiyikast
qasdtialhdredmttlnaakvasekayklakiapekidvaevhdcfainglilvedlgf
ckkgdagkvidegkdyddfvtvnpsgglkaaghalgatgirqvgelywqlkqdkeckdrq
atikngygiaanvggtggtvcvhllsdkr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6et9D (D:)
mrdvaiigygqtkfgelwedsfrdliveagvkaikdanvdggdidamyignmsgglfvgq
ehiasliadhaglnpvpctrveaacasgslalrsavlsvasghhdvvlaggvekmtdved
ataaiasasdqeweaffgatfpslyammarrymyqygltieelsmwsviahenatknkya
qfgfkttleqvmnaspvadpltlmhcspvsdgasalivcdadkaeefapkdeiiyikast
qasdtialhdredmttlnaakvasekayklakiapekidvaevhdcfainglilvedlgf
ckkgdagkvidegkiridyddfvtvnpsgglkaaghalgatgirqvgelywqlkqdkeck
drqatikngygiaanvggtggtvcvhllsdkr

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6et9E (E:)
mvvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysiv
yappkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiis
ygykfvpite

    Sequence, based on observed residues (ATOM records):
    >6et9E (E:)
vvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysivy
appkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiisy
gykfvpit

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6et9F (F:)
mvvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysiv
yappkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiis
ygykfvpite

    Sequence, based on observed residues (ATOM records):
    >6et9F (F:)
vvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysivy
appkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiisy
gykfvpit

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6et9G (G:)
mvvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysiv
yappkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiis
ygykfvpite

    Sequence, based on observed residues (ATOM records):
    >6et9G (G:)
vvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysivy
appkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiisy
gykfvpit

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6et9H (H:)
mvvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysiv
yappkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiis
ygykfvpite

    Sequence, based on observed residues (ATOM records):
    >6et9H (H:)
vvrswrhmkerynligtrcktcgkvyfpsrtvcpdcrrkgeleefqlsgkgkiytysivy
appkefnkltpyviaiveleegpkvtaqvdcdinkisigipveaafrrikedgkdgiisy
gykfvpit

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6et9I (I:)
mkdigivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaa
rnavkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtag
iqmcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngty
syttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqp
ngkfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygs
gagsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

    Sequence, based on observed residues (ATOM records):
    >6et9I (I:)
digivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaarn
avkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtagiq
mcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngtysy
ttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqpng
kfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygsga
gsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6et9J (J:)
mkdigivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaa
rnavkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtag
iqmcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngty
syttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqp
ngkfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygs
gagsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

    Sequence, based on observed residues (ATOM records):
    >6et9J (J:)
kdigivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaar
navkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtagi
qmcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngtys
yttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqpn
gkfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygsg
agsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6et9K (K:)
mkdigivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaa
rnavkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtag
iqmcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngty
syttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqp
ngkfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygs
gagsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

    Sequence, based on observed residues (ATOM records):
    >6et9K (K:)
digivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaarn
avkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtagiq
mcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngtysy
ttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqpng
kfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygsga
gsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6et9L (L:)
mkdigivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaa
rnavkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtag
iqmcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngty
syttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqp
ngkfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygs
gagsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki

    Sequence, based on observed residues (ATOM records):
    >6et9L (L:)
digivgygsyipkyrikveeiakvwgkdpeaikkglvvneksvpspdedtatiaveaarn
avkraginaekigavyvgseshpyavkptsatvaeaigatpdltaadlefackagtagiq
mcmglvgsglieygmaigadtaqgapgdaleytasaggaayiignkkdemiavfngtysy
ttdtpdfwrregqsypkhggrftgepayfkhvlnaakgimekmgttvkdydycvfhqpng
kfyikaakslgftneqykyglltpylgntysgavplglsnildhaeegarilavsygsga
gsdafditvterikevvdkapktldllnrkkyidyavyvkyrgkiki