PDB entry 6esm

View 6esm on RCSB PDB site
Description: Crystal structure of MMP9 in complex with inhibitor BE4.
Class: hydrolase
Keywords: metzincin, carboxylate inhibitor alternative zinc-binding groups, HYDROLASE
Deposited on 2017-10-23, released 2018-05-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-16, with a file datestamp of 2018-05-11.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: N/A
AEROSPACI score: 0.72 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Matrix metalloproteinase-9,Matrix metalloproteinase-9
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP9, CLG4B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14780 (Start-106)
    • Uniprot P14780 (107-159)
      • engineered mutation (117)
    Domains in SCOPe 2.07: d6esma_
  • Heterogens: B9Z, ZN, CA, PZE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6esmA (A:)
    fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
    fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgvgyslflvaahqfg
    halgldhssvpealmypmyrftegpplhkddvngirhlyg
    

    Sequence, based on observed residues (ATOM records): (download)
    >6esmA (A:)
    gdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviqfg
    vaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgvgyslflvaahqfgha
    lgldhssvpealmypmyrftegpplhkddvngirhlyg