PDB entry 6erh

View 6erh on RCSB PDB site
Description: complex of xlf and heterodimer ku bound to dna
Deposited on 2017-10-18, released 2018-10-17
The last revision was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: X-ray repair cross-complementing protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: XRCC6, G22P1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: X-ray repair cross-complementing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: XRCC5, G22P2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13010 (18-End)
      • initiating methionine (0)
      • expression tag (1-17)
  • Chain 'C':
    Compound: X-ray repair cross-complementing protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: XRCC6, G22P1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: X-ray repair cross-complementing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: XRCC5, G22P2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13010 (18-End)
      • initiating methionine (0)
      • expression tag (1-17)
  • Chain 'F':
    Compound: DNA (34-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'K':
    Compound: DNA (21-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'M':
    Compound: Non-homologous end-joining factor 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: DNA (34-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'R':
    Compound: DNA (21-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'T':
    Compound: Non-homologous end-joining factor 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6erhA (A:)
msgwesyyktegdeeaeeeqeenleasgdykysgrdsliflvdaskamfesqsedeltpf
dmsiqciqsvyiskiissdrdllavvfygtekdknsvnfkniyvlqeldnpgakrileld
qfkgqqgqkrfqdmmghgsdyslsevlwvcanlfsdvqfkmshkrimlftnednphgnds
akasrartkagdlrdtgifldlmhlkkpggfdislfyrdiisiaededlrvhfeesskle
dllrkvraketrkralsrlklklnkdivisvgiynlvqkalkpppiklyretnepvktkt
rtfntstgglllpsdtkrsqiygsrqiilekeeteelkrfddpglmlmgfkplvllkkhh
ylrpslfvypeeslvigsstlfsallikclekevaalcrytprrnippyfvalvpqeeel
ddqkiqvtppgfqlvflpfaddkrkmpftekimatpeqvgkmkaiveklrftyrsdsfen
pvlqqhfrnlealaldlmepeqavdltlpkveamnkrlgslvdefkelvyppdynpegkv
tkrk

    Sequence, based on observed residues (ATOM records):
    >6erhA (A:)
grdsliflvdaskamfesdeltpfdmsiqciqsvyiskiissdrdllavvfygtekdkns
vnfkniyvlqeldnpgakrileldqfkgqqgqkrfqdmmghgsdyslsevlwvcanlfsd
shkrimlftnednphgndsakasrartkagdlrdtgifldlmhlkkpggfdislfyrdii
siaedrvhfeesskledllrkvraketrkralsrlklklnkdivisvgiynlvqkalkpp
piklyretnepvktktrtfntstgglllpsdtkrsqiygsrqiilekeeteelkrfddpg
lmlmgfkplvllkkhhylrpslfvypeeslvigsstlfsallikclekevaalcrytprr
nippyfvalvpqeeelddqkiqvtppgfqlvflpfaddkrkmpftekimatpeqvgkmka
iveklrftyrsdsfenpvlqqhfrnlealaldlmepeqavdltlpkveamnkrlgslvde
fkelvyppdy

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6erhB (B:)
mhhhhhhhhhhenlyfqgvrsgnkaavvlcmdvgftmsnsipgiespfeqakkvitmfvq
rqvfaenkdeialvlfgtdgtdnplsggdqyqnitvhrhlmlpdfdlledieskiqpgsq
qadfldalivsmdviqhetigkkfekrhieiftdlssrfsksqldiiihslkkcdislqf
flpfslgkedgsgdrgdgpfrlgghgpsfplkgiteqqkegleivkmvmislegedglde
iysfseslrklcvfkkierhsihwpcrltigsnlsiriaayksilqervkktwtvvdakt
lkkediqketvyclndddetevlkediiqgfrygsdivpfskvdeeqmkyksegkcfsvl
gfckssqvqrrffmgnqvlkvfaarddeaaavalsslihalddldmvaivryaydkranp
qvgvafphikhnyeclvyvqlpfmedlrqymfsslknskkyapteaqlnavdalidsmsl
akkdektdtledlfpttkipnprfqrlfqcllhralhpreplppiqqhiwnmlnppaevt
tksqiplskiktlfplieakkkdqvtaqeifq

    Sequence, based on observed residues (ATOM records):
    >6erhB (B:)
mhhhhhhhhhhenlyfqgvrsgnkaavvlcmdvgftmsnsipgiespfeqakkvitmfvq
rqvfaenkdeialvlfgtdgtdnplsggdqyqnitvhrhlmlpdfdlledieskiqpgsq
qadfldalivsmdviqhetigkkfekrhieiftdlssrfsksqldiiihslkkcdislqf
flpfslggiteqqkegleivkmvmislegedgldeiysfseslrklcvfkkierhsihwp
crltigsnlsiriaayksilqervkktwtvvdaktlkkediqketvyclndddetevlke
diiqgfrygsdivpfskvdeeqmkyksegkcfsvlgfckssqvqrrffmgnqvlkvfaar
ddeaaavalsslihalddldmvaivryaydkranpqvgvafphikhnyeclvyvqlpfme
dlrqymfsslknskkyapteaqlnavdalidsmslakkdektdtledlfpttkipnprfq
rlfqcllhralhpreplppiqqhiwnmlnppaevttksqiplskiktlfpliea

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6erhC (C:)
msgwesyyktegdeeaeeeqeenleasgdykysgrdsliflvdaskamfesqsedeltpf
dmsiqciqsvyiskiissdrdllavvfygtekdknsvnfkniyvlqeldnpgakrileld
qfkgqqgqkrfqdmmghgsdyslsevlwvcanlfsdvqfkmshkrimlftnednphgnds
akasrartkagdlrdtgifldlmhlkkpggfdislfyrdiisiaededlrvhfeesskle
dllrkvraketrkralsrlklklnkdivisvgiynlvqkalkpppiklyretnepvktkt
rtfntstgglllpsdtkrsqiygsrqiilekeeteelkrfddpglmlmgfkplvllkkhh
ylrpslfvypeeslvigsstlfsallikclekevaalcrytprrnippyfvalvpqeeel
ddqkiqvtppgfqlvflpfaddkrkmpftekimatpeqvgkmkaiveklrftyrsdsfen
pvlqqhfrnlealaldlmepeqavdltlpkveamnkrlgslvdefkelvyppdynpegkv
tkrk

    Sequence, based on observed residues (ATOM records):
    >6erhC (C:)
grdsliflvdaskamfesqdeltpfdmsiqciqsvyiskiissdrdllavvfygtekdkn
svnfkniyvlqeldnpgakrileldqfkgqqgqkrfqdmmghgsdyslsevlwvcanlfs
dvqmshkrimlftnednphgndsakasrartkagdlrdtgifldlmhlkkpggfdislfy
rdiisiaervhfeesskledllrkvraketrkralsrlklklnkdivisvgiynlvqkal
kpppiklyretnepvktktrtfntstgglllpsdtkrsqiygsrqiilekeeteelkrfd
dpglmlmgfkplvllkkhhylrpslfvypeeslvigsstlfsallikclekevaalcryt
prrnippyfvalvpqeeelddqkiqvtppgfqlvflpfaddkrkmpftekimatpeqvgk
mkaiveklrftyrsdsfenpvlqqhfrnlealaldlmepeqavdltlpkveamnkrlgsl
vdefkelvyppdy

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6erhD (D:)
mhhhhhhhhhhenlyfqgvrsgnkaavvlcmdvgftmsnsipgiespfeqakkvitmfvq
rqvfaenkdeialvlfgtdgtdnplsggdqyqnitvhrhlmlpdfdlledieskiqpgsq
qadfldalivsmdviqhetigkkfekrhieiftdlssrfsksqldiiihslkkcdislqf
flpfslgkedgsgdrgdgpfrlgghgpsfplkgiteqqkegleivkmvmislegedglde
iysfseslrklcvfkkierhsihwpcrltigsnlsiriaayksilqervkktwtvvdakt
lkkediqketvyclndddetevlkediiqgfrygsdivpfskvdeeqmkyksegkcfsvl
gfckssqvqrrffmgnqvlkvfaarddeaaavalsslihalddldmvaivryaydkranp
qvgvafphikhnyeclvyvqlpfmedlrqymfsslknskkyapteaqlnavdalidsmsl
akkdektdtledlfpttkipnprfqrlfqcllhralhpreplppiqqhiwnmlnppaevt
tksqiplskiktlfplieakkkdqvtaqeifq

    Sequence, based on observed residues (ATOM records):
    >6erhD (D:)
mhhhhhhhhhhenlyfqgvrsgnkaavvlcmdvgftmsnsipgiespfeqakkvitmfvq
rqvfaenkdeialvlfgtdgtdnplsggdqyqnitvhrhlmlpdfdlledieskiqpgsq
qadfldalivsmdviqhetigkkfekrhieiftdlssrfsksqldiiihslkkcdislqf
flpfslggiteqqkegleivkmvmislegedgldeiysfseslrklcvfkkierhsihwp
crltigsnlsiriaayksilqervkktwtvvdaktlkkediqketvyclndddetevlke
diiqgfrygsdivpfskvdeeqmkyksegkcfsvlgfckssqvqrrffmgnqvlkvfaar
ddeaaavalsslihalddldmvaivryaydkranpqvgvafphikhnyeclvyvqlpfme
dlrqymfsslknskkyapteaqlnavdalidsmslakkdektdtledlfpttkipnprfq
rlfqcllhralhpreplppiqqhiwnmlnppaevttksqiplskiktlfplieak

  • Chain 'F':
    No sequence available.

  • Chain 'K':
    No sequence available.

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6erhM (M:)
lqrpqlskvkrkkprglfs

    Sequence, based on observed residues (ATOM records):
    >6erhM (M:)
kprglfs

  • Chain 'O':
    No sequence available.

  • Chain 'R':
    No sequence available.

  • Chain 'T':
    Sequence, based on SEQRES records:
    >6erhT (T:)
lqrpqlskvkrkkprglfs

    Sequence, based on observed residues (ATOM records):
    >6erhT (T:)
prglfs