PDB entry 6eos

View 6eos on RCSB PDB site
Description: dpp8 - apo, space group 19
Deposited on 2017-10-10, released 2018-02-07
The last revision was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Dipeptidyl peptidase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP8, DPRP1, MSTP097, MSTP135, MSTP141
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6eosA (A:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6eosA (A:)
lepfyveryswsqlkklladtrkyhkaphdfmfvkrndpdgphsdriyylamsentlfys
eipktinraavlmlswkplldlgiasydyhqgsgtflfqagsgiyhvkdggpqgftqqpl
rpnlvetscpnirmdpklcpadpdwiafihsndiwisnivtreerrltyvhnelanmeed
arsagvatfvlqeefdrysgywwcpkaettpsggkilrilyeendeseveiihvtspmle
trradsfrypktgtanpkvtfkmseimidaegriidvidkeliqpfeilfegveyiarag
wtpegkyawsilldrsqtrlqivlispelfipveddvmerqrliesvpdsvtpliiyeet
tdiwinihdifhvfpqsheeeiefifasecktgfrhlykitsilkeskykrssgglpaps
dfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfegtkdsplehhlyvvsyvnpge
vtrltdrgyshsccisqhcdffiskysnqknphcvslyklsspeddptcktkefwatild
sagplpdytppeifsfesttgftlygmlykphdlqpgkkyptvlfiyggpqvqlvnnrfk
gvkyfrlntlaslgyvvvvidnrgschrglkfegafkykmgqieiddqveglqylasryd
fidldrvgihgwsyggylslmalmqrsdifrvaiagapvtlwifydtgyterymghpdqn
eqgyylgsvamqaekfpsepnrllllhgfldenvhfahtsillsflvragkpydlqiypq
erhsirvpesgehyelhllhylqenlgsriaalkv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6eosB (B:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6eosB (B:)
lepfyveryswsqlkklladtrkaphdfmfvkrndpdgphsdriyylamentlfyseipk
tinraavlmlswkplldlgiasydyhqgsgtflfqagsgiyhvkdggpqgftqqplrpnl
vetscpnirmdpklcpadpdwiafihsndiwisnivtreerrltyvhnelanmeedarsa
gvatfvlqeefdrysgywwcpkaettpsggkilrilyeendeseveiihvtspmletrra
dsfrypktgtanpkvtfkmseimidaegriidvidkeliqpfeilfegveyiaragwtpe
gkyawsilldrsqtrlqivlispelfipveddvmerqrliesvpdsvtpliiyeettdiw
inihdifhvfpqsheeeiefifasecktgfrhlykitsilkeskykrssgglpapsdfkc
pikeeiaitsgewevlgrhgsniqvdevrrlvyfegtkdsplehhlyvvsyvnpgevtrl
tdrgyshsccisqhcdffiskysnqknphcvslyklsspeddptcktkefwatildsagp
lpdytppeifsfesttgftlygmlykphdlqpgkkyptvlfiyggpqvqlvnnrfkgvky
frlntlaslgyvvvvidnrgschrglkfegafkykmgqieiddqveglqylasrydfidl
drvgihgwsyggylslmalmqrsdifrvaiagapvtlwifydtgyterymghpdqneqgy
ylgsvamqaekfpsepnrllllhgfldenvhfahtsillsflvragkpydlqiypqerhs
irvpesgehyelhllhylqenlgsriaalkv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6eosC (C:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6eosC (C:)
lepfyveryswsqlkklladtrkykaphdfmfvkrndpdgphsdriyylamsentlfyse
ipktinraavlmlswkplldlfqellrerkrigtvgiasydyhqgsgtflfqagsgiyhv
kdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisnivtreerrl
tyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilrilyeendes
eveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvidkeliqpfe
ilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvmerqrliesv
pdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhlykitsilkes
kykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfegtkdsple
hhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvslyklsspeddp
tcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgkkyptvlfiy
ggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafkykmgqieidd
qveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagapvtlwifydt
gyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfahtsillsflv
ragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6eosD (D:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6eosD (D:)
lepfyveryswsqlkklladtrmakaphdfmfvkrndpdgphsdriyylamsentlfyse
ipktinraavlmlswkplldlfgiasydyhqgsgtflfqagsgiyhvkdggpqgftqqpl
rpnlvetscpnirmdpklcpadpdwiafihsndiwisnivtreerrltyvhnelanmeed
arsagvatfvlqeefdrysgywwcpkaettpsggkilrilyeendeseveiihvtspmle
trradsfrypktgtanpkvtfkmseimidaegriidvidkeliqpfeilfegveyiarag
wtpegkyawsilldrsqtrlqivlispelfipveddvmerqrliesvpdsvtpliiyeet
tdiwinihdifhvfpqsheeeiefifasecktgfrhlykitsilkeskykrssgglpaps
dfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfegtkdsplehhlyvvsyvnpge
vtrltdrgyshsccisqhcdffiskysnqknphcvslyklsspeddptcktkefwatild
sagplpdytppeifsfesttgftlygmlykphdlqpgkkyptvlfiyggpqvqlvnnrfk
gvkyfrlntlaslgyvvvvidnrgschrglkfegafkykmgqieiddqveglqylasryd
fidldrvgihgwsyggylslmalmqrsdifrvaiagapvtlwifydtgyterymghpdqn
eqgyylgsvamqaekfpsepnrllllhgfldenvhfahtsillsflvragkpydlqiypq
erhsirvpesgehyelhllhylqenlgsriaalkv

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6eosE (E:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6eosE (E:)
lepfyveryswsqlkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsen
tlfyseipktinraavlmlswkplldlfqatlgiasydyhqgsgtflfqagsgiyhvkdg
gpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisnivtreerrltyv
hnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilrilyeendeseve
iihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvidkeliqpfeilf
egveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvmerqrliesvpds
vtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhlykitsilkeskyk
rssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfegtkdsplehhl
yvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvslyklsspeddptck
tkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgkkyptvlfiyggp
qvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafkykmgqieiddqve
glqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagapvtlwifydtgyt
erymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfahtsillsflvrag
kpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkv

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6eosF (F:)
mwkrseqmkiksgkcnmaaameteqlgveifetadceeniesqdrpklepfyveryswsq
lkklladtrkyhgymmakaphdfmfvkrndpdgphsdriyylamsgenrentlfyseipk
tinraavlmlswkplldlfqatldygmysreeellrerkrigtvgiasydyhqgsgtflf
qagsgiyhvkdggpqgftqqplrpnlvetscpnirmdpklcpadpdwiafihsndiwisn
ivtreerrltyvhnelanmeedarsagvatfvlqeefdrysgywwcpkaettpsggkilr
ilyeendeseveiihvtspmletrradsfrypktgtanpkvtfkmseimidaegriidvi
dkeliqpfeilfegveyiaragwtpegkyawsilldrsqtrlqivlispelfipveddvm
erqrliesvpdsvtpliiyeettdiwinihdifhvfpqsheeeiefifasecktgfrhly
kitsilkeskykrssgglpapsdfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyf
egtkdsplehhlyvvsyvnpgevtrltdrgyshsccisqhcdffiskysnqknphcvsly
klsspeddptcktkefwatildsagplpdytppeifsfesttgftlygmlykphdlqpgk
kyptvlfiyggpqvqlvnnrfkgvkyfrlntlaslgyvvvvidnrgschrglkfegafky
kmgqieiddqveglqylasrydfidldrvgihgwsyggylslmalmqrsdifrvaiagap
vtlwifydtgyterymghpdqneqgyylgsvamqaekfpsepnrllllhgfldenvhfah
tsillsflvragkpydlqiypqerhsirvpesgehyelhllhylqenlgsriaalkvi

    Sequence, based on observed residues (ATOM records):
    >6eosF (F:)
lepfyveryswsqlkklladtrkyhkaphdfmfvkrndpdgphsdriyylamsentlfys
eipktinraavlmlswkplldlgiasydyhqgsgtflfqagsgiyhvkdggpqgftqqpl
rpnlvetscpnirmdpklcpadpdwiafihsndiwisnivtreerrltyvhnelanmeed
arsagvatfvlqeefdrysgywwcpkaettpsggkilrilyeendeseveiihvtspmle
trradsfrypktgtanpkvtfkmseimidaegriidvidkeliqpfeilfegveyiarag
wtpegkyawsilldrsqtrlqivlispelfipveddvmerqrliesvpdsvtpliiyeet
tdiwinihdifhvfpqsheeeiefifasecktgfrhlykitsilkeskykrssgglpaps
dfkcpikeeiaitsgewevlgrhgsniqvdevrrlvyfegtkdsplehhlyvvsyvnpge
vtrltdrgyshsccisqhcdffiskysnqknphcvslyklsspeddptcktkefwatild
sagplpdytppeifsfesttgftlygmlykphdlqpgkkyptvlfiyggpqvqlvnnrfk
gvkyfrlntlaslgyvvvvidnrgschrglkfegafkykmgqieiddqveglqylasryd
fidldrvgihgwsyggylslmalmqrsdifrvaiagapvtlwifydtgyterymghpdqn
eqgyylgsvamqaekfpsepnrllllhgfldenvhfahtsillsflvragkpydlqiypq
erhsirvpesgehyelhllhylqenlgsriaalkv