PDB entry 6eo7

View 6eo7 on RCSB PDB site
Description: x-ray structure of the complex between human alpha-thrombin and modified 15-mer dna aptamer containing 5-(3-(acetamide-n-yl)-1- propen-1-yl)-2'-deoxyuridine residue
Deposited on 2017-10-09, released 2017-10-18
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: GA68B2 - modified human thrombin binding aptamer
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'H':
    Compound: Prothrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Prothrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: K, 0G6, NA, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'D':
    No sequence available.

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6eo7H (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6eo7L (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records):
    >6eo7L (L:)
geadcglrplfekksledkterellesyid