PDB entry 6enx

View 6enx on RCSB PDB site
Description: Zebrafish Sirt5 in complex with stalled bicyclic intermediate of inhibitory compound 10
Class: signaling protein
Keywords: Hydrolase, PTM, inhibitor, Sirtuin, SIGNALING PROTEIN
Deposited on 2017-10-06, released 2017-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent protein deacylase sirtuin-5, mitochondrial
    Species: Danio rerio [TaxId:7955]
    Gene: sirt5, si:ch211-121a2.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6enxa_
  • Heterogens: ZN, DMS, BJW, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6enxA (A:)
kmtrpssdltafrehfakakhiaiitgagvsaesgvptfrgpggfwrkwqaqdlatpeaf
srdpslvwefyhyrrevmrskmpnpahlaiaecearlgqqgrsvviitqnidelhhrags
khvyeihgslfktrcmscgevkanhkspicpaldgkgapdpntkearipvellprcerks
cngllrphvvwfgetldsdiltaverelekcdlclvvgtssivypaamfapqvasrgvpv
aefnmectpatqrfkyhfegpcgstlppale

    Sequence, based on observed residues (ATOM records): (download) 
    >6enxA (A:)
pssdltafrehfakakhiaiitgagvsaesgvptfrgpggfwrkwqaqdlatpeafsrdp
slvwefyhyrrevmrskmpnpahlaiaecearlgqqgrsvviitqnidelhhragskhvy
eihgslfktrcmscgevkanhkspicpaldgkgapdpntkearipvellprcerkscngl
lrphvvwfgetldsdiltaverelekcdlclvvgtssivypaamfapqvasrgvpvaefn
mectpatqrfkyhfegpcgstlppale