PDB entry 6enq

View 6enq on RCSB PDB site
Description: Structure of human PPAR gamma LBD in complex with Lanifibranor (IVA337)
Class: transcription
Keywords: Nuclear hormone receptor, PPARgamma modulator, Lanifibranor, TRANSCRIPTION
Deposited on 2017-10-06, released 2018-03-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6enqa_
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6enqb_
  • Heterogens: BJB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6enqA (A:)
    eissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnsl
    mmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqv
    tllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfn
    alelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakl
    lqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
    

    Sequence, based on observed residues (ATOM records): (download)
    >6enqA (A:)
    lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgkevai
    rifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgv
    lisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpg
    llnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikkt
    etdmslhpllqeiykd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6enqB (B:)
    eissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnsl
    mmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqv
    tllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfn
    alelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakl
    lqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
    

    Sequence, based on observed residues (ATOM records): (download)
    >6enqB (B:)
    esadlralakhlydsyiksfpltkakarailtspfviydmnslmmgeevairifqgcqfr
    sveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfm
    treflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpied
    iqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpl
    lqeiykd