PDB entry 6el9

View 6el9 on RCSB PDB site
Description: glucocorticoid receptor in complex with azd9567
Deposited on 2017-09-28, released 2018-02-21
The last revision was dated 2018-03-21, with a file datestamp of 2018-03-16.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucocorticoid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NR3C1, GRL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04150
      • engineered mutation (73)
      • engineered mutation (104)
      • engineered mutation (140)
      • engineered mutation (186)
      • engineered mutation (214)
  • Chain 'B':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDO, B9W, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6el9A (A:)
gsiqqattgvsqetsenpgdktivpatlpqltptlvslleviepevlyagydssvpdstw
rimttlnmlggrqmiaavkwakaipgfrnlhlddqmtllqyswmslmafalgwrsyrqss
anllcfapdliineqrmtlpdmydqckhmlyvsselhrlqvsyeeylcmktllllssvpk
dglksqalfdeirmtyikelgkaivkregnssqnsqrfyqltklldsmhevvenllnycf
qtfldktmsiefpemlaeiitnqipkysngnikkllfhqk

    Sequence, based on observed residues (ATOM records):
    >6el9A (A:)
ptlvslleviepevlyagydssvpdstwrimttlnmlggrqmiaavkwakaipgfrnlhl
ddqmtllqyswmslmafalgwrsyrqssanllcfapdliineqrmtlpdmydqckhmlyv
sselhrlqvsyeeylcmktllllssvpkdglksqalfdeirmtyikelgkaivkregnss
qnsqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysngni
kkllfhq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6el9B (B:)
kenallrylldkdd

    Sequence, based on observed residues (ATOM records):
    >6el9B (B:)
enallrylldkdd