PDB entry 6ekn
View 6ekn on RCSB PDB site
Description: Crystal structure of MMP12 in complex with inhibitor BE7.
Class: hydrolase
Keywords: metzincin, carboxylate inhibitor alternative zinc-binding groups, HYDROLASE
Deposited on
2017-09-26, released
2018-05-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-06-06, with a file datestamp of
2018-06-01.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.65
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12, HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (1-158)
- initiating methionine (0)
- engineered mutation (66)
Domains in SCOPe 2.08: d6ekna1, d6ekna2 - Heterogens: ZN, CA, B9N, EDO, HOH