PDB entry 6ekm

View 6ekm on RCSB PDB site
Description: crystal structure of mammalian rev7 in complex with human rev3 second binding site
Deposited on 2017-09-26, released 2018-10-10
The last revision was dated 2018-10-10, with a file datestamp of 2018-10-05.
Experiment type: XRAY
Resolution: 2.76 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitotic spindle assembly checkpoint protein MAD2B
    Species: Mus musculus [TaxId:10090]
    Gene: Mad2l2, Mad2b, Rev7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9D752
      • engineered mutation (10-11)
      • engineered mutation (131-132)
      • engineered mutation (134)
  • Chain 'B':
    Compound: DNA polymerase zeta catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: REV3L, POLZ, REV3
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ekmA (A:)
    mttltrqdlnsaqvvadvlseflevavhlilyvrevypvgifqkrkkynvpvqmschpel
    nqyiqdtlhcvkpllekndvekvvvvildkehrpvekfvfeitqppllsinsdsllshve
    qllrafilkiskvdkvldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvh
    mhdprliplktmtsdilkmqlyveerahkns
    

    Sequence, based on observed residues (ATOM records):
    >6ekmA (A:)
    lnsaqvvadvlseflevavhlilyvrevypvgifqkrkkynvpvqmschpelnqyiqdtl
    hcvkpllekndvekvvvvildkehrpvekfvfeitqppllsinsdsllshveqllrafil
    kiskvdkvldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvhmhdprlip
    lktmtsdilkmqlyveera
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ekmB (B:)
    mgdkkivimpckcapsrqlvqvwlqake
    

    Sequence, based on observed residues (ATOM records):
    >6ekmB (B:)
    dkkivimpckcapsrqlvqvwlqak