PDB entry 6ekd

View 6ekd on RCSB PDB site
Description: Crystal structure of JNK3 in complex with a pyridinylimidazole inhibitor
Class: transferase
Keywords: Protein Kinase Activity Map Kinase Activity ATP Binding Protein Phosphorylation, TRANSFERASE
Deposited on 2017-09-26, released 2018-08-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-08, with a file datestamp of 2018-08-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ekda_
  • Heterogens: B9K, BME, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6ekdA (A:)
    ggsmskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikkl
    srpfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcq
    viqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartag
    tsfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkv
    ieqlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardl
    lskmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliy
    kevmnse
    

    Sequence, based on observed residues (ATOM records): (download)
    >6ekdA (A:)
    nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
    krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
    msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglvtryyrapevilgmg
    ykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyve
    nrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyi
    nvwydderehtieewkeliykevmn