PDB entry 6ek6

View 6ek6 on RCSB PDB site
Description: Crystal structure of KDM5B in complex with S49195a.
Class: oxidoreductase
Keywords: KDM5B, oxidoreductase
Deposited on 2017-09-25, released 2018-03-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-14, with a file datestamp of 2018-03-09.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific demethylase 5B,Lysine-specific demethylase 5B
    Species: Homo sapiens [TaxId:9606]
    Gene: KDM5B, JARID1B, PLU1, RBBP2H1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGL1 (1-74)
      • initiating methionine (0)
    • Uniprot Q9UGL1 (75-454)
    Domains in SCOPe 2.08: d6ek6a1, d6ek6a2, d6ek6a3
  • Heterogens: 90V, ZN, MN, NI, DMS, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ek6A (A:)
mflpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhft
priqrlneleaqtrvrdytlrtfgemadafksdyfnmpvhmvptelvekefwrlvstiee
dvtveygadiaskefgsgfpvrdgkiklspeeeeyldsgwnlnnmpvmeqsvlahitadi
cgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkklap
elfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfaea
vnfctvdwlplgrqcvehyrllhrycvfshdemickmaskadvldvvvastvqkdmaimi
edekalretvrklgvidsermdfellpdderqcvkckttcfmsaiscsckpgllvclhhv
kelcscppykyklryrytlddlypmmnalklraes

    Sequence, based on observed residues (ATOM records): (download) 
    >6ek6A (A:)
mflpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhft
priqrlneleaqtrvrdytlrtfgemadafksdyfnmpvhmvptelvekefwrlvstiee
dvtveygadiasfgsgfpvrdiklspeeeeyldsgwnlnnmpvmeqsvlahitadicgmk
lpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkklapelfv
sqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfaeavnfc
tvdwlplgrqcvehyrllhrycvfshdemickmaskadvldvvvastvqkdmaimiedek
alretvrklgvidsermdfellpdderqcvkckttcfmsaiscsckpgllvclhhvkelc
scppykyklryrytlddlypmmnalklraes