PDB entry 6eim

View 6eim on RCSB PDB site
Description: Human STK10 bound to GW683134A
Class: transferase
Keywords: kinase, inhibitor, complex, LOK, TRANSFERASE
Deposited on 2017-09-19, released 2017-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: STK10, LOK
    Database cross-references and differences (RAF-indexed):
    • Uniprot O94804 (Start-301)
      • conflict (232)
      • conflict (235)
      • conflict (256)
    Domains in SCOPe 2.08: d6eima_
  • Chain 'B':
    Compound: serine/threonine-protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: STK10, LOK
    Database cross-references and differences (RAF-indexed):
    • Uniprot O94804 (Start-301)
      • conflict (232)
      • conflict (235)
      • conflict (256)
    Domains in SCOPe 2.08: d6eimb_
  • Heterogens: B6E, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6eimA (A:)
smrksreyehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeel
edyiveieilatcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiq
vvcrqmlealnflhskriihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigt
pywmapevvmcetmkdtpydykadiwslgitliemaqiepphhelnpmrvllaiaasdpp
tlltpskwsvefrdflaialdknpetrpsaaqllehpfvssitsnkalrelvaeakaevm
ee

    Sequence, based on observed residues (ATOM records): (download) 
    >6eimA (A:)
vrrdldpnevweivgelkvykaknketgalaaakvietkseeeledyiveieilatcdhp
yivkllgayyhdgklwimiefcpggavdaimleldrgltepqiqvvcrqmlealnflhsk
riihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigtpywmapevvmcetmkd
tpydykadiwslgitliemaqiepphhelnpmrvllaiaasdpptlltpskwsvefrdfl
aialdknpetrpsaaqllehpfvssitsnkalrelvaeakaevmee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6eimB (B:)
smrksreyehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeel
edyiveieilatcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiq
vvcrqmlealnflhskriihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigt
pywmapevvmcetmkdtpydykadiwslgitliemaqiepphhelnpmrvllaiaasdpp
tlltpskwsvefrdflaialdknpetrpsaaqllehpfvssitsnkalrelvaeakaevm
ee

    Sequence, based on observed residues (ATOM records): (download) 
    >6eimB (B:)
yehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeeledyivei
eilatcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiqvvcrqml
ealnflhskriihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigtpywmape
vvmcetmkdtpydykadiwslgitliemaqiepphhelnpmrvllaiaasdpptlltpsk
wsvefrdflaialdknpetrpsaaqllehpfvssitsnkalrelvaeakaevmee