PDB entry 6eil

View 6eil on RCSB PDB site
Description: dyrk1a in complex with xmd8-49
Deposited on 2017-09-19, released 2018-08-29
The last revision was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dyrk1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13627 (3-367)
      • expression tag (0-2)
  • Chain 'B':
    Compound: dyrk1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13627 (3-367)
      • expression tag (0-2)
  • Chain 'C':
    Compound: dyrk1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13627 (3-367)
      • expression tag (0-2)
  • Chain 'D':
    Compound: dyrk1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13627 (3-367)
      • expression tag (0-2)
  • Heterogens: B6B, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6eilA (A:)
gasdsshkkerkvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveq
ewvaikiiknkkaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemls
ynlydllrntnfrgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsa
ikivdfgsscqlgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfs
ganevdqmnkivevlgippahildqapkarkffeklpdgtwnlkktkdgkreykppgtrk
lhnilgvetggpggrragesghtvadylkfkdlilrmldydpktriqpyyalqhsffkkt
adegtnts

    Sequence, based on observed residues (ATOM records):
    >6eilA (A:)
kvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveqewvaikiiknk
kaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemlsynlydllrntn
frgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsaikivdfgsscq
lgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfsganevdqmnki
vevlgippahildqapkarkffeklpdgtwnlkkteykppgtrklhnilgvetggpggrr
agesghtvadylkfkdlilrmldydpktriqpyyalqhsffk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6eilB (B:)
gasdsshkkerkvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveq
ewvaikiiknkkaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemls
ynlydllrntnfrgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsa
ikivdfgsscqlgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfs
ganevdqmnkivevlgippahildqapkarkffeklpdgtwnlkktkdgkreykppgtrk
lhnilgvetggpggrragesghtvadylkfkdlilrmldydpktriqpyyalqhsffkkt
adegtnts

    Sequence, based on observed residues (ATOM records):
    >6eilB (B:)
rkvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveqewvaikiikn
kkaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemlsynlydllrnt
nfrgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsaikivdfgssc
qlgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfsganevdqmnk
ivevlgippahildqapkarkffeklpdgtwnlkykppgtrklhnilgvetggpggrrag
esghtvadylkfkdlilrmldydpktriqpyyalqhsffk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6eilC (C:)
gasdsshkkerkvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveq
ewvaikiiknkkaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemls
ynlydllrntnfrgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsa
ikivdfgsscqlgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfs
ganevdqmnkivevlgippahildqapkarkffeklpdgtwnlkktkdgkreykppgtrk
lhnilgvetggpggrragesghtvadylkfkdlilrmldydpktriqpyyalqhsffkkt
adegtnts

    Sequence, based on observed residues (ATOM records):
    >6eilC (C:)
vyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveqewvaikiiknkk
aflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemlsynlydllrntnf
rgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsaikivdfgsscql
gqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfsganevdqmnkiv
evlgippahildqapkarkffwnlkkreykppgtrklhnilgvetggpggrragesghtv
adylkfkdlilrmldydpktriqpyyalqhsff

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6eilD (D:)
gasdsshkkerkvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveq
ewvaikiiknkkaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemls
ynlydllrntnfrgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsa
ikivdfgsscqlgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfs
ganevdqmnkivevlgippahildqapkarkffeklpdgtwnlkktkdgkreykppgtrk
lhnilgvetggpggrragesghtvadylkfkdlilrmldydpktriqpyyalqhsffkkt
adegtnts

    Sequence, based on observed residues (ATOM records):
    >6eilD (D:)
kvyndgydddnydyivkngekwmdryeidsligkgsfgqvvkaydrveqewvaikiiknk
kaflnqaqievrllelmnkhdtemkyyivhlkrhfmfrnhlclvfemlsynlydllrntn
frgvslnltrkfaqqmctallflatpelsiihcdlkpenillcnpkrsaikivdfgsscq
lgqriyqyiqsrfyrspevllgmpydlaidmwslgcilvemhtgeplfsganevdqmnki
vevlgippahildqapkarkffeklpdgtwnlkkykppgtrklhnilgvetggpggghtv
adylkfkdlilrmldydpktriqpyyalqhsff