PDB entry 6ehr

View 6ehr on RCSB PDB site
Description: The crystal structure of the human LAMTOR-RagA CTD-RagC CTD complex
Class: signaling protein
Keywords: Scaffolding complex, Rag-GTPases, mTOR, Ragulator, mTORC1, SIGNALING PROTEIN
Deposited on 2017-09-14, released 2017-10-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Ragulator complex protein LAMTOR3
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR3, MAP2K1IP1, MAPKSP1, PRO2783
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9UHA4
  Domains in SCOPe 2.08: d6ehra_
• Chain 'B':
  Compound: Ragulator complex protein LAMTOR2
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR2, MAPBPIP, ROBLD3, HSPC003
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9Y2Q5 (2-125)
    • initiating methionine (0)
    • expression tag (1)
  Domains in SCOPe 2.08: d6ehrb1, d6ehrb2
• Chain 'C':
  Compound: Ragulator complex protein LAMTOR5
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR5, HBXIP, XIP
  Database cross-references and differences (RAF-indexed):
  • Uniprot O43504 (0-90)
• Chain 'D':
  Compound: Ragulator complex protein LAMTOR4
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR4, C7orf59
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q0VGL1 (0-End)
• Chain 'E':
  Compound: Ragulator complex protein LAMTOR1
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR1, C11orf59, PDRO, PP7157
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6IAA8
• Chain 'F':
  Compound: Ras-related GTP-binding protein A
  Species: Homo sapiens [TaxId:9606]
  Gene: RRAGA
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q7L523 (1-End)
    • expression tag (0)
• Chain 'G':
  Compound: Ras-related GTP-binding protein C
  Species: Homo sapiens [TaxId:9606]
  Gene: RRAGC
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9HB90 (2-End)
    • expression tag (1)

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >6ehrA (A:)
  gahmaddlkrflykklpsveglhaivvsdrdgvpvikvandnapehalrpgflstfalat
  dqgsklglsknksiicyyntyqvvqfnrlplvvsfiasssantglivslekelaplfeel
  rqvvevs
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6ehrA (A:)
  ddlkrflykklpsveglhaivvsdrdgvpvikvandnapehalrpgflstfalatdqgsk
  lglsknksiicyyntyqvvqfnrlplvvsfiasssantglivslekelaplfeelrqvve
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6ehrB (B:)
  mglrpkaltqvlsqantggvqstlllnnegsllaysgygdtdarvtaaiasniwaaydrn
  gnqafnednlkfilmdcmegrvaitrvanlllcmyaketvgfgmlkakaqalvqyleepl
  tqvaas
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  No sequence available.
  
  
• Chain 'G':
  No sequence available.