PDB entry 6ega

View 6ega on RCSB PDB site
Description: IRAK4 in complex with a type II inhibitor
Class: transferase/transferase inhibitor
Keywords: Inhibitor, Complex, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2018-08-19, released 2019-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6egaa_
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6egab_
  • Heterogens: J8A, SO4, CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6egaA (A:)
gamgsenkslevsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnt
tvavkklaamvditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympng
slldrlscldgtpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakis
dfglarasekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavd
ehrepqllldikeeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdik
kvqqllqemtas

    Sequence, based on observed residues (ATOM records): (download) 
    >6egaA (A:)
hsfsfyelknvtnnfderpisvggnkmgeggvvykgyvnnttvavkkltteelkqqfdqe
ikvmakcqhenlvellgfssddlclvyvympngslldrlscldgtpplswhmrckiaqga
anginflhenhhihrdiksanilldeaftakisdfvgttaymapealrgeitpksdiysf
gvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamysva
sqclhekknkrpdikkvqqllqemta

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6egaB (B:)
gamgsenkslevsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnt
tvavkklaamvditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympng
slldrlscldgtpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakis
dfglarasekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavd
ehrepqllldikeeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdik
kvqqllqemtas

    Sequence, based on observed residues (ATOM records): (download) 
    >6egaB (B:)
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaalkqqfd
qeikvmakcqhenlvellgfssdgdlclvyvympngslldrlscldgtpplswhmrckia
qgaanginflhenhhihrdiksanilldeaftakisdfvgttaymapealrgeitpksdi
ysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamy
svasqclhekknkrpdikkvqqllqemta