PDB entry 6efh

View 6efh on RCSB PDB site
Description: Pyruvate decarboxylase from Kluyveromyces lactis soaked with pyruvamide
Class: lyase
Keywords: pyruvate decarboxylase, thiamine diphosphate, substrate activation, pyruvamide, LYASE
Deposited on 2018-08-16, released 2018-08-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 2.99 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate decarboxylase
    Species: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) [TaxId:284590]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6efha1, d6efha2, d6efha3
  • Chain 'B':
    Compound: pyruvate decarboxylase
    Species: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) [TaxId:284590]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6efhb1, d6efhb2, d6efhb3
  • Heterogens: PY0, TPP, MG, 1PE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6efhA (A:)
mseitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadg
yarlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgng
dftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasl
ldtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqf
pafvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsys
yktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneava
dstplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierli
hgetaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievml
ptmdapsnlvkqaqltaatnakn

    Sequence, based on observed residues (ATOM records): (download) 
    >6efhA (A:)
seitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadgy
arlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgngd
ftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasll
dtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqfp
afvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsysy
ktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneavad
stplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttga
tlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierlih
getaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievmlp
tmdapsnlvkqaqltaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6efhB (B:)
mseitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadg
yarlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvssqakqlllhhtlgng
dftvfhrmssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpasl
ldtpidlslkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqf
pafvtpmgkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsys
yktknivefhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneava
dstplkqewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierli
hgetaqynciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievml
ptmdapsnlvkqaqltaatnakn

    Sequence, based on observed residues (ATOM records): (download) 
    >6efhB (B:)
seitlgrylferlkqvevqtifglpgdfnlslldniyevpgmrwagnanelnaayaadgy
arlkgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsvsslhhtlgngdftvfhr
mssnisettamitdintapaeidrcirttyvsqrpvylglpanlvdltvpaslldtpidl
slkpndpeaeeevienvlqlikeaknpviladaccsrhdakaetkklidltqfpafvtpm
gkgsidekhprfggvyvgtlsspavkeavesadlvlsvgallsdfntgsfsysyktkniv
efhsdytkirsatfpgvqmkfalqklltkvadaakgykpvpvpsepehneavadstplkq
ewvwtqvgeflregdvvitetgtsafginqthfpnntygisqvlwgsigfttgatlgaaf
aaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytierlihgetaqy
nciqnwqhlellptfgakdyeavrvsttgewnklttdekfqdntrirlievmlptmdaps
nlvkqaqltaatnakn