SCOPe 2.08: Structural Classification of Proteins

PDB entry 6ee2

View 6ee2 on RCSB PDB site
Description: x-ray crystal structure of pf-m17 in complex with inhibitor 6i and regulatory zinc ion
Deposited on 2018-08-13, released 2018-12-26
The last revision was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (0-End)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'B':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'C':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (Start-520)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'D':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (0-End)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'E':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'F':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'G':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (0-End)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'H':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (Start-520)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'I':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (Start-520)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
  - expression tag (521-523)
Chain 'J':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (0-End)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'K':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
Chain 'L':
Compound: Pf-M17
Species: Plasmodium falciparum NF135/5.C10 [TaxId:1036726]
Gene: PFNF135_05834
Database cross-references and differences (RAF-indexed):
- Uniprot W4I9J7 (Start-520)
  - engineered mutation (67)
  - engineered mutation (430)
  - engineered mutation (461)
  - expression tag (521)
Heterogens: J1V, CO3, ZN, SO4, 1PE, DMS, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6ee2A (A:)
asevpqvvsldptsipieyntpihdikvqvydikggcnveegltiflvnnpgkengpvki
sskvndkqvseflkdenmekfnvklgtskhfymfndnknsvavgyvgcgsvadlseadmk
rvvlslvtmlhdnklskltvvfeinvdknlfrffletlfyeymtderfkstdknvnmeyi
khlgvyinnadtykeevekarvyyfgtyyasqliaapsnycnpvslsnaavelaqklnle
ykilgvkeleelkmgaylsvgkgsmypnkfihltykskgdvkkkialvgkgitfdsggyn
lkaapgsmidlmkfdmsgcaavlgcaycvgtlkpenveihflsavcenmvsknsyrpgdi
itasngktievgntdaegrltladalvyaeklgvdyivdiatltgamlyslgtsyagvfg
nneelinkilqssktsnepvwwlpiineyratlnskyadinqisssvkassivaslflke
fvqntawahidiagvswnfkarkpkgfgvrlltefvlndalhhhhh