PDB entry 6edc

View 6edc on RCSB PDB site
Description: hcgas-16bp dsdna complex
Deposited on 2018-08-09, released 2019-05-29
The last revision was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: CGAS, C6orf150, MB21D1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N884
      • engineered mutation (142-144)
  • Chain 'B':
    Compound: DNA (5'-d(*ap*ap*ap*tp*tp*gp*cp*cp*gp*ap*ap*gp*ap*cp*gp*ap*a)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'C':
    Compound: DNA (5'-d(*tp*tp*cp*gp*tp*cp*tp*tp*cp*gp*gp*cp*ap*ap*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6edcA (A:)
daapgasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyye
hvkisapnefdvmfklevpriqleeysntrayyfvkfkrnpkenplsqflegeilsaskm
lskfrkiikeeindikdtdvimeaerggspavtllisekisvditlalesksswpastqe
glriqnwlsakvrkqlrlkpfylvpkhakegngfqeetwrlsfshiekeilnnhgksktc
cenkeekccrkdclklmkylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwd
rkdlglcfdncvtyflqclrteklenyfipefnlfssnlidkrskefltkqieyernnef
pvfdef

    Sequence, based on observed residues (ATOM records):
    >6edcA (A:)
gasklravleklklsrddistaagmvkgvvdhlllrlkcdsafrgvgllntgsyyehvki
sapnefdvmfklevpriqleeysntrayyfvkfknplsqflegeilsaskmlskfrkiik
eeindidvimeaerggspavtllisekisvditlalesksswpastqeglriqnwlsakv
rkqlrlkpfylvpkhaqeetwrlsfshiekeilnnhgksktccenkeekccrkdclklmk
ylleqlkerfkdkkhldkfssyhvktaffhvctqnpqdsqwdrkdlglcfdncvtyflqc
lrteklenyfipefnlfssnlidkrskefltkqieyernnefpvfde

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.