PDB entry 6e6x

View 6e6x on RCSB PDB site
Description: The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 1-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxy-2-methylpyridin-4(1H)-one
Class: hydrolase/hydrolase inhibitor
Keywords: PA endonuclease, inhibitor, influenza, H1N1, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2018-07-25, released 2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (6-End)
      • expression tag (4-5)
      • conflict (57)
    Domains in SCOPe 2.08: d6e6xa1, d6e6xa2
  • Heterogens: HWM, MN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6e6xA (A:)
mgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgsg
dpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrre
vhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasrs
lwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6e6xA (A:)
mamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfghrfeii
egrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankie
kthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqser