PDB entry 6dvl

View 6dvl on RCSB PDB site
Description: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-115
Class: hydrolase/hydrolase inhibitor
Keywords: histone deacetylaase, metallohydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2018-06-24, released 2018-08-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dvla_
  • Chain 'B':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dvlb_
  • Heterogens: ZN, K, HBG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6dvlA (A:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6dvlA (A:)
    itglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelalc
    hsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqvr
    navaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqhi
    feeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaaf
    hhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliile
    ggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6dvlB (B:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6dvlB (B:)
    pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
    chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
    rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
    ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
    fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
    eggynltsisesmsmctsmllgdsppsldtplktsatvsinnvlrahapfwsslr