PDB entry 6dne

View 6dne on RCSB PDB site
Description: Crystal structure of human Bromodomain-containing protein 4 (BRD4) bromodomain with MS660
Class: transcription
Keywords: transcription, inhibitor, histone acetylation
Deposited on 2018-06-06, released 2018-07-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-07-18, with a file datestamp of 2018-07-13.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dnea_
  • Chain 'B':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: H1V, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6dneA (A:)
    nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
    pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
    lpteeteimivqakgrgrgrketgtakpgvstvpnttqastppqtqtpqpnpppvqatph
    pfpavtpdlivqtpvmtvvppqplqtpppvppqpqpppapapqpvqshppiiaatpqpvk
    tkkgvkrkadtttpttidpiheppslppepkttklgqrressrpvkppkkdvpdsqqhpa
    peksskvseqlkccsgilkemfakkhaayawpfykpvdvealglhdycdiikhpmdmsti
    kskleareyrdaqefgadvrlmfsncykynppdhevvamarklqdvfemrfakmpdepee
    pvvavsspavpppt
    

    Sequence, based on observed residues (ATOM records): (download)
    >6dneA (A:)
    nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
    pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
    lpte
    

  • Chain 'B':
    No sequence available.