PDB entry 6dml

View 6dml on RCSB PDB site
Description: A multiconformer ligand model of 3,5 dimethylisoxaxole bound to the bromodomain of human BRD4
Class: transcription/transcription inhibitor
Keywords: Complex, multiconformer model, TRANSCRIPTION, transcription-transcription inhibitor complex
Deposited on 2018-06-05, released 2018-12-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.08: d6dmla1, d6dmla2
• Heterogens: 9BM, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6dmlA (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee