PDB entry 6dgp
View 6dgp on RCSB PDB site
Description: Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide
Class: transcription
Keywords: Nuclear receptors, TZDs, Drug design, Therapeutic targets, TRANSCRIPTION
Deposited on
2018-05-17, released
2019-05-22
The last revision prior to the SCOPe 2.07 freeze date was dated
2019-05-22, with a file datestamp of
2019-05-17.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6dgpa_ - Chain 'B':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6dgpb_ - Chain 'C':
Compound: TRAP220 Coactivator Peptide (Mediator of RNA polymerase II transcription subunit 1)
Species: Homo sapiens [TaxId:9606]
Gene: MED1
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: TRAP220 Coactivator Peptide (Mediator of RNA polymerase II transcription subunit 1)
Species: Homo sapiens [TaxId:9606]
Gene: MED1
Database cross-references and differences (RAF-indexed):
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6dgpA (A:)
mahhhhhhvddddkmenlyfqgqlnpesadlralakhlydsyiksfpltkakarailtgk
ttdkspfviydmnslmmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteya
ksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpf
gdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelq
lklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
Sequence, based on observed residues (ATOM records): (download)
>6dgpA (A:)
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdmslhpllqeiykdl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6dgpB (B:)
mahhhhhhvddddkmenlyfqgqlnpesadlralakhlydsyiksfpltkakarailtgk
ttdkspfviydmnslmmgedkikfkhitplqeqskevairifqgcqfrsveavqeiteya
ksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpf
gdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelq
lklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
Sequence, based on observed residues (ATOM records): (download)
>6dgpB (B:)
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdmslhpllqeiykdl
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.