PDB entry 6ddj

View 6ddj on RCSB PDB site
Description: Crystal Structure of the human BRD2 BD2 bromodimain in complex with a Tetrahydroquinoline analogue
Class: Transcription/Inhibitor
Keywords: BET, BRD2, bromodomain, Inhibitor, Complex, Transcription, Transcription-Inhibitor complex
Deposited on 2018-05-10, released 2019-11-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 1.05 Å
R-factor: N/A
AEROSPACI score: 0.78 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD2, KIAA9001, RING3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25440 (7-114)
      • expression tag (0-6)
    Domains in SCOPe 2.07: d6ddja1, d6ddja2
  • Heterogens: G7V, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6ddjA (A:)