PDB entry 6dc6

View 6dc6 on RCSB PDB site
Description: Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin
Class: signaling protein/ligase
Keywords: Ubiquitin, E1, adenylation, thioester bond, E2, transthiolation, SIGNALING PROTEIN, SIGNALING PROTEIN-LIGASE complex
Deposited on 2018-05-04, released 2018-10-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-10-10, with a file datestamp of 2018-10-05.
Experiment type: XRAY
Resolution: 3.14 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-like modifier-activating enzyme 1
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA1, A1S9T, UBE1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22314 (5-End)
      • engineered mutation (588)
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dc6b_
  • Chain 'C':
    Compound: Ubiquitin-like modifier-activating enzyme 1
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA1, A1S9T, UBE1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22314 (5-End)
      • engineered mutation (588)
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6dc6d_
  • Heterogens: MG, POP

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6dc6B (B:)
    gamamqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtl
    sdyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >6dc6B (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6dc6D (D:)
    gamamqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtl
    sdyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >6dc6D (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg