PDB entry 6d96

View 6d96 on RCSB PDB site
Description: Structure of influenza neuraminidase from strain A/BrevigMission/1/1918(H1N1) expressed in HEK-293E cells
Class: hydrolase
Keywords: 6-bladed beta-propeller, glycoprotein, glycosidase, hydrolase, membrane, metal-binding, signal-anchor, transmembrane, virion
Deposited on 2018-04-27, released 2019-05-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96a_
  • Chain 'B':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96b_
  • Chain 'C':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96c_
  • Chain 'D':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96d_
  • Chain 'E':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96e_
  • Chain 'F':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96f_
  • Chain 'G':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96g_
  • Chain 'H':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:88776]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6d96h_
  • Heterogens: NAG, CA, GOL, FUC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6d96A (A:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96A (A:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6d96B (B:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96B (B:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6d96C (C:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96C (C:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6d96D (D:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96D (D:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >6d96E (E:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96E (E:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >6d96F (F:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96F (F:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >6d96G (G:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96G (G:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >6d96H (H:)
    hhhhhhslvprgspsrsviltgnsslcpisgwaiyskdngirigskgdvfvirepfiscs
    hlecrtffltqgallndkhsngtvkdrspyrtlmscpvgeapspynsrfesvawsasach
    dgmgwltigisgpdngavavlkyngiitdtikswrnnilrtqesecacvngscftimtdg
    psngqasykilkiekgkvtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvs
    fdqnldyqigyicsgvfgdnprpndgtgscgpvssngangikgfsfrydngvwigrtkst
    ssrsgfemiwdpngwtetdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwve
    lirgqpkentiwtsgssisfcgvnsdtvgwswpdgaelpfsidk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6d96H (H:)
    viltgnsslcpisgwaiyskdngirigskgdvfvirepfiscshlecrtffltqgallnd
    khsngtvkdrspyrtlmscpvgeapspynsrfesvawsasachdgmgwltigisgpdnga
    vavlkyngiitdtikswrnnilrtqesecacvngscftimtdgpsngqasykilkiekgk
    vtksielnapnyhyeecscypdtgkvmcvcrdnwhgsnrpwvsfdqnldyqigyicsgvf
    gdnprpndgtgscgpvssngangikgfsfrydngvwigrtkstssrsgfemiwdpngwte
    tdssfsvrqdivaitdwsgysgsfvqhpeltgldcmrpcfwvelirgqpkentiwtsgss
    isfcgvnsdtvgwswpdgaelpfsid