PDB entry 6cw8

View 6cw8 on RCSB PDB site
Description: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with RTS-V5
Class: hydrolase
Keywords: Histone deacetylase, metallohydrolase, HYDROLASE
Deposited on 2018-03-30, released 2018-11-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-11-21, with a file datestamp of 2018-11-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6cw8a_
  • Chain 'B':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6cw8b_
  • Heterogens: ZN, K, FGY, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6cw8A (A:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6cw8A (A:)
    pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
    chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
    rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
    ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
    fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
    eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwssl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6cw8B (B:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >6cw8B (B:)
    pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
    chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
    rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
    ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
    fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
    eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr