PDB entry 6cw7

View 6cw7 on RCSB PDB site
Description: E. coli DHFR product complex with (6S)-5,6,7,8-TETRAHYDROFOLATE
Class: oxidoreductase
Keywords: DHFR, dihydrofolate reductase, tetrahydrofolate, complex, OXIDOREDUCTASE
Deposited on 2018-03-30, released 2019-01-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-09, with a file datestamp of 2019-01-04.
Experiment type: XRAY
Resolution: 1.03 Å
R-factor: N/A
AEROSPACI score: 0.78 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [TaxId:199310]
    Gene: folA, c0058
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0ABQ5 (0-158)
      • expression tag (159-161)
    Domains in SCOPe 2.07: d6cw7a1, d6cw7a2
  • Heterogens: THG, CL, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6cw7A (A:)
    misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
    ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
    gdthfpdyepddwesvfsefhdadaqnshsycfeilerrhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6cw7A (A:)
    misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
    ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
    gdthfpdyepddwesvfsefhdadaqnshsycfeilerrhhh