PDB entry 6cks

View 6cks on RCSB PDB site
Description: Crystal Structure of BRD4 with QC4956
Class: gene regulation/inhibitor
Keywords: BRD4, Acetyllysine, epigenetics, GENE REGULATION-INHIBITOR complex
Deposited on 2018-02-28, released 2018-05-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-02, with a file datestamp of 2018-04-27.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (1-125)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d6cksa1, d6cksa2
  • Heterogens: F5Y, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6cksA (A:)
    mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
    tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
    elptee